The Design and Analysis of Sequential Clinical Trials (Ellis Horwood Series in Mathematics and Its Applications)

Whitehead, John

ISBN 10: 0470273550 / ISBN 13: 9780470273555

Published by Horwood Publishing Limited, 1983

About this Item

Seller Inventory # 394706998

Bibliographic Details

• Title: The Design and Analysis of Sequential Clinical Trials (Ellis Horwood Series in Mathematics and Its Applications)
• Publisher: Horwood Publishing Limited
• Publication Date: 1983
• Language: English
• ISBN 10: 0470273550
• ISBN 13: 9780470273555
• Binding: Soft cover
• Condition: Used

About this title

Synopsis

This book details all aspects of sequential clinical trials from preliminary planning, through the monitoring of the trial, to the final analysis of the results. Emphasis is placed on the triangular test and other procedures based on straight line stopping boundaries. These methods allow for frequent or occasional interim analyses and permit the analysis of a wide variety of patient responses. Alternative procedures are also covered in detail, and these include –spending function methods, repeated confidence intervals and Bayesian approaches to sequential clinical trials.

Review

"...This book is clear, it provides many details and is well written..." (Statistical Methods in Medical Research, No.11, 2002)