Computer Modelling in Molecular Biology - Softcover

 
9783527300624: Computer Modelling in Molecular Biology

Synopsis

This text provides an introduction to the use of computer simulation techniques as applied to problems in molecular biology. The book focuses on a number of key applications in order to study macromolecular conformation, flexibility and interactions of biomolecules (such as peptides, proteins and nucleic acids). Besides the introduction (which gives a broad overview of the topic), each of the seven chapters show one example of an important application area in detail. The interdisciplinary approach of the book makes it equally suitable for molecular biologists, biochemists and biophysicians.

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From the Back Cover

Computer Modelling in Molecular Biology Edited by Julia M. Goodfellow This book supplies an application-oriented introduction to molecular simulation techniques used to study a wide range of problems in molecular biology. Each chapter focuses in detail on one kind of application, including the scientific background, the appropriate methodology and the relationship to experimental results. The book contains many areas of interest to basic and industrial scientists, including:

  • flexibility of peptides
  • protein-peptide interactions
  • ion translocation across membranes
  • modelling protein and nucleic acid conformations
  • stability of mutant proteins
  • modelling conformational transitions
Currently the only up-to-date compilation available, this book enables readers to get an overview of the methods and how they are used in various specialized applications without having to search for them in a large number of papers in different journals.

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