Genome Analysis: A Practical Approach (Practical Approach Series) - Softcover

Davies, K. E.

Softcover

ISBN 10: 1852211105 ISBN 13: 9781852211103

Publisher: Oxford University Press, 1989

Synopsis

Methodologies used to analyse the genomes of prokaryotes and eukaryotes are advancing very rapidly as it has been realized that there is a resolution gap between what can be viewed under the microscope and what molecular techniques can resolve. This book presents current, successful strategies for construction of physical maps to identify and analyse the arrangement and function of genes. These techniques, which are applicable to a range of organisms, are being used to move from linked markers to candidate genes in several human monogenic disorders. They are presented in a way that should enable any research or diagnostic laboratory to apply them to their particular systems. Also included are descriptions of new probes and approaches for the localization of human disorders whose analysis has so far eluded the molecular geneticist.

About this title

Synopsis

Includes: Techniques for mammalian genome transfer; genome mapping by restriction fingerprinting; pulsed field gel electrophoresis and the technology of large DNA molecules; chromosome jumping; the polymerase chain reaction; DNA fingerprinting; mapping complex genetic traits in humans

Edition details

• Publisher: Oxford University Press
• Publication date: 1989
• Language: English
• ISBN 10: 1852211105
• ISBN 13: 9781852211103
• Binding: Paperback
• Number of pages: 250