Protein Structure and Function: Primers in Biology - Softcover

Petsko, Gregory; Ringe, Dagmar

Softcover

ISBN 10: 1405119225 ISBN 13: 9781405119221

Publisher: Wiley-Blackwell, 2003

Synopsis

Protein Structure and Function considers the key concepts of protein structure and function and the relationship between sequence, structure and function with clear, concise explanations and full colour illustrations.

• Written by two outstanding names in the field, Gregory Petsko and Dagmar Ringe.
  
• Considers the principles of protein structure and folding, functional properties of proteins and regulation of protein function, and introduces the basic principles whereby structure and function are deduced from sequence.
  
• Fully up–to–date with emphasis on what sequence can tell you about structure and function.
  
• Ideal for undergraduates and graduates studying the fundamental principles of protein structure and function in departments of biochemistry and molecular biology, and working scientists needing an up–to–date introduction to the field.
  
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  All 240 illustrations from Protein Structure and Function are available on the web as jpgs and downloadable tifs for teaching, at http://www.new–science–press.com/browse/protein/resources/

SPECIAL OFFER:

For instructors adopting the book for courses with enrolments of ten or more students we offer free access to the following online resources:

• the full text online for a year, for personal use only
  
• updates – revised, expanded, or new sections and updated references available online only
  
• PowerPoint functionality allowing instructors to compile any selection of illustrations into a slide show
  
• interactive true–false and multiple–choice self–test questions with answers

About this title

Review

"...a valuable addition to the subject. It combines much important basic material in one volume, but also offers a contemporary angle through its discussion of structural and functional genomics." Mark Parsons, University of Leeds "I particularly like how many topics are introduced in a two page piece, with the significant publications referenced on the same page." Brian Bahnson, University of Delaware "...an excellent teaching resoure for undergraduates ... covers a broad range of topics in this expanding field...This book definitely achieves its goal of being easy to learn from. All the elements are there..." Catherine Brean, University College London, IJBCB, January 2004

From the Back Cover

Introducing a new cutting edge book on protein structure and function that is an ideal introduction for students and a must for all reading lists.

Protein Structure and Function considers the key concepts of protein structure and function and the relationship between sequence, structure and function with clear, concise explanations and full colour illustrations.

• Written by two outstanding names in the field, Gregory Petsko and Dagmar Ringe
  
• Considers the principles of protein structure and folding, functional properties of proteins and regulation of protein function, and introduces the basic principles whereby structure and function are deduced from sequence
  
• Fully up–to–date with emphasis on what sequence can tell you about structure and function

The book is divided into five chapters:

Chapter 1 – From Sequence to Structure – introduces the principles of protein structure and folding, with the emphasis on the biophysical properties of proteins that determine their folding and structure

Chapter 2 –From Structure to Function – describes the principles of the main biochemical functions of proteins, namely binding and catalysis, with a short section on the properties of structural proteins

Chapter 3 – Control of Protein Function – focuses on the regulation of protein function and contains concise descriptions of all of the regulatory mechanisms that operate on proteins, from PH to phosphorylation, with several sections on protein switches based on nucleotide hydrolysis

Chapter 4 – From Sequence to Function – introduces the basic principles whereby structure and function are deduced from sequence, with illustrative examples

Chapter 5 – Structure Determination – outlines the methodology of X–ray crystallography and NMR spectroscopy and how data collected by these methods are interpreted.

Resources for Instructors

All the 240 illustrations from Protein Structure and Function are available on the web as jpgs and downloadable tifs for teaching, at http://www.new–science–press.com/browse/protein/resources/

Edition details

• Publisher: Wiley-Blackwell
• Publication date: 2003
• ISBN 10: 1405119225
• ISBN 13: 9781405119221
• Binding: Paperback
• Language: English
• Edition number: 1
• Number of pages: 180