The Identities of Membrane Steroid Receptors: ...And Other Proteins Mediating Nongenomic Steroid Action - Hardcover
Synopsis
The nature of rapid (nongenomic) steroid signaling has been re-probed with experimental tools. Cellular responses to steroids start with membrane-initiated signals, eventually culminating in major transcriptional commitment and overhaul of cellular components. While much is known about the execution of the ultimate decision, little is known about how reception and processing of the first steroid signal notifies the cell of impending change. Therefore, it is very important to establish the identity of the proteins initiating these cellular responses. This text juxtaposes identifications from different laboratories and presents several possibilities: nuclear steroid receptor-like forms in non-nuclear locations, other known membrane receptors or channels with additional steroid binding sites, enzymes, transporters, receptors for serum steroid-binding proteins, and unique, previously undescribed proteins.
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Synopsis
Understanding the nature of rapid (nongenomic) steroid signaling depends upon identifying the protein(s) which binds hormone at the cell periphery and mediates the initial signal transmission. This book juxtaposes identifications from different laboratories and collectively presents several possibilities: nuclear steroid receptors in nonnuclear locations, other known membrane receptors with additional steroid binding sites, enzymes, transporters, receptors for blood-borne steroid-binding proteins, and unique, previously undescribed proteins.
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The Identities of Membrane Steroid Receptors
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Springer US, Springer New York Feb 2003, 2003
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Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Cheryl S. Watson University o/Texas Medical Branch Cellular steroid action has been thoroughly studied in the nuclear compartment. However, nuclear steroid receptor mechanisms have been unable to explain some of the rapid activities of steroids, partiCUlarly those which occur in a time frame of seconds to minutes [reviewed in (1;2)]. Based on these and other considerations, an alternative membrane-associated receptor form was long ago proposed to exist (3). Others interpret the location of the steroid receptors mediating these rapid effects as peri membrane or cytoplasmic. New experimental tools have been brought to bear on the topic of receptors for steroids which mediate non-genomic actions, and thus investigative activity and focus regarding this type of steroid receptor has recently increased significantly. However, there may be multiple answers to the question 'how do steroids mediate rapid nongenomic effects ' Steroid actions initiated at the cell membrane can impinge on important phases in the lifespan of a cell: proliferation, migration, differentiation, and release of hormones or neurotransmitters functioning as signals to other cells. 224 pp. Englisch. Seller Inventory # 9781402073441
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Gebunden. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Cheryl S. Watson University o/Texas Medical Branch Cellular steroid action has been thoroughly studied in the nuclear compartment. However, nuclear steroid receptor mechanisms have been unable to explain some of the rapid activities of steroids, partiCUlarl. Seller Inventory # 4095013
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The Identities of Membrane Steroid Receptors | .And Other Proteins Mediating Nongenomic Steroid Action
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Buch. Condition: Neu. The Identities of Membrane Steroid Receptors | .And Other Proteins Mediating Nongenomic Steroid Action | Cheryl S. Watson | Buch | xiv | Englisch | 2003 | Springer | EAN 9781402073441 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu Print on Demand. Seller Inventory # 102572745
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The Identities of Membrane Steroid Receptors
Published by
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ISBN 13: 9781402073441
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Buch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Cheryl S. Watson University o/Texas Medical Branch Cellular steroid action has been thoroughly studied in the nuclear compartment. However, nuclear steroid receptor mechanisms have been unable to explain some of the rapid activities of steroids, partiCUlarly those which occur in a time frame of seconds to minutes [reviewed in (1;2)]. Based on these and other considerations, an alternative membrane-associated receptor form was long ago proposed to exist (3). Others interpret the location of the steroid receptors mediating these rapid effects as peri membrane or cytoplasmic. New experimental tools have been brought to bear on the topic of receptors for steroids which mediate non-genomic actions, and thus investigative activity and focus regarding this type of steroid receptor has recently increased significantly. However, there may be multiple answers to the question 'how do steroids mediate rapid nongenomic effects ' Steroid actions initiated at the cell membrane can impinge on important phases in the lifespan of a cell: proliferation, migration, differentiation, and release of hormones or neurotransmitters functioning as signals to other cells.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 224 pp. Englisch. Seller Inventory # 9781402073441