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Diuretics: Basic, Pharmacological, and Clinical Aspects: Proceedings of the International Meeting on Diuretics, Sorrento, Italy, May 26–30, 1986: 18 (Developments in Nephrology, 18) - Hardcover
Synopsis
The need for adequate means by which to improve urine output is very old. Even in the "Scuola Salernitana", the oldest medieval medical school in Western Europe, about 1000 years ago it was taught how to improve urine output. The list of known "diuretica" included herbs, plants, roots, vegetables, in particular asparagus, fennel and carrot. The first diuretic drugs, however, were mercurial compounds. Thus, calomel, mercurous chloride, was initially used as a diuretic in the sixteenth century by Paracelsus, being one of the ingredients of the so-called "Guy's Hospital pill". But calomel had a cathartic effect so that it was replaced by organic mercurial compounds. These diuretics were clearly toxic. After the discovery of the car bonic anhydrase, in the early 1930s, and the introduction of sulfanilamide as a chemotherapeutic agent, it was observed that this drug was inhibiting carbonic anhydrase in vitro and urinary acidification in vivo thereby causing metabolic acidosis; urine output, however, appeared to increase. Subsequent studies led to the synthesis of more potent analogs, in particular acetazolamide. Studies on car bonic anhydrase inhibitors led to the synthesis of benzothiadiazides which disclosed much less inactivating action on carbonic anhydrase and much more diuretic effect through an inhibition of tubular transport of sodium and chloride. Chlorothiazide was the first member of this class of diuretics. Thiazides are still used in clinical practice.
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Diuretics: Basic, Pharmacological, and Clinical Aspects
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15.88 cm x 3.81 cm x 24.13 cm. Condition: Gut. 1. Auflage. 576 Seiten Proceedings of the International Meeting on Diuretics, Sorrento, Italy, May 2630, 1986. (Developments in Nephrology, 18, Band 18) Innen sauberer, guter Zustand. Hardcover, Pappeinband, mit den üblichen Bibliotheks-Markierungen, Stempeln und Einträgen, innen wie außen, siehe Bilder. (Evtl. auch Kleber- und/oder Etikettenreste, sowie -abdrücke durch abgelöste Bibliotheksschilder). DE-10-01 Sprache: Englisch Gewicht in Gramm: 1208. Seller Inventory # 2052727
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Diuretics: Basic, Pharmacological, and Clinical Aspects: Proceedings of the International Meeting on Diuretics, Sorrento, Italy, May 26?30, 1986 (Developments in Nephrology, 18)
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Hardcover. Condition: New. In shrink wrap. Looks like an interesting title! Seller Inventory # Q-0898388856
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Diuretics: Basic, Pharmacological, and Clinical Aspects
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Proceedings of the International Meeting on Diuretics, Sorrento, Italy, May 26-30, 1986 The need for adequate means by which to improve urine output is very old. Even in the Scuola Salernitana , the oldest medieval medical school in Western Europe, ab. Seller Inventory # 5982553
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Diuretics: Basic, Pharmacological, and Clinical Aspects Canton, Antonia Dal und V.E. Andreucci
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Condition: gut. 1987. Diuretics: Basic, Pharmacological, and Clinical Aspects In englischer Sprache. pages. Seller Inventory # BN734451
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Diuretics: Basic, Pharmacological, and Clinical Aspects
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Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The need for adequate means by which to improve urine output is very old. Even in the 'Scuola Salernitana', the oldest medieval medical school in Western Europe, about 1000 years ago it was taught how to improve urine output. The list of known 'diuretica' included herbs, plants, roots, vegetables, in particular asparagus, fennel and carrot. The first diuretic drugs, however, were mercurial compounds. Thus, calomel, mercurous chloride, was initially used as a diuretic in the sixteenth century by Paracelsus, being one of the ingredients of the so-called 'Guy's Hospital pill'. But calomel had a cathartic effect so that it was replaced by organic mercurial compounds. These diuretics were clearly toxic. After the discovery of the car bonic anhydrase, in the early 1930s, and the introduction of sulfanilamide as a chemotherapeutic agent, it was observed that this drug was inhibiting carbonic anhydrase in vitro and urinary acidification in vivo thereby causing metabolic acidosis; urine output, however, appeared to increase. Subsequent studies led to the synthesis of more potent analogs, in particular acetazolamide. Studies on car bonic anhydrase inhibitors led to the synthesis of benzothiadiazides which disclosed much less inactivating action on carbonic anhydrase and much more diuretic effect through an inhibition of tubular transport of sodium and chloride. Chlorothiazide was the first member of this class of diuretics. Thiazides are still used in clinical practice. 636 pp. Englisch. Seller Inventory # 9780898388855
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Diuretics: Basic, Pharmacological, and Clinical Aspects | Proceedings of the International Meeting on Diuretics, Sorrento, Italy, May 26-30, 1986
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Buch. Condition: Neu. Diuretics: Basic, Pharmacological, and Clinical Aspects | Proceedings of the International Meeting on Diuretics, Sorrento, Italy, May 26-30, 1986 | Antonia Dal Canton (u. a.) | Buch | Developments in Nephrology | lvi | Englisch | 1987 | Springer US | EAN 9780898388855 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu Print on Demand. Seller Inventory # 102503645
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Diuretics: Basic, Pharmacological, and Clinical Aspects: Proceedings of the International Meeting on Diuretics, Sorrento, Italy, May 26-30, 1986 (Developments in Nephrology, 18)
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Diuretics
Published by
Kluwer Academic Publishers, 1987
ISBN 10: 0898388856
ISBN 13: 9780898388855
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Hardcover
Seller: Kennys Bookshop and Art Galleries Ltd., Galway, GY, Ireland
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Condition: New. Proceedings of the International Meeting on Diuretics, Sorrento, Italy, May 26-30, 1986 Editor(s): Andreucci, Vittorio E.; Canton, A.Dal. Series: Developments in Nephrology. Num Pages: 576 pages, black & white illustrations. BIC Classification: MJR. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly. Dimension: 235 x 155 x 34. Weight in Grams: 1061. . 1987. Hardback. . . . . Seller Inventory # V9780898388855
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Diuretics: Basic, Pharmacological, and Clinical Aspects
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Springer US, Springer US Mai 1987, 1987
ISBN 10: 0898388856
ISBN 13: 9780898388855
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Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germany
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Buch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The need for adequate means by which to improve urine output is very old. Even in the 'Scuola Salernitana', the oldest medieval medical school in Western Europe, about 1000 years ago it was taught how to improve urine output. The list of known 'diuretica' included herbs, plants, roots, vegetables, in particular asparagus, fennel and carrot. The first diuretic drugs, however, were mercurial compounds. Thus, calomel, mercurous chloride, was initially used as a diuretic in the sixteenth century by Paracelsus, being one of the ingredients of the so-called 'Guy's Hospital pill'. But calomel had a cathartic effect so that it was replaced by organic mercurial compounds. These diuretics were clearly toxic. After the discovery of the car bonic anhydrase, in the early 1930s, and the introduction of sulfanilamide as a chemotherapeutic agent, it was observed that this drug was inhibiting carbonic anhydrase in vitro and urinary acidification in vivo thereby causing metabolic acidosis; urine output, however, appeared to increase. Subsequent studies led to the synthesis of more potent analogs, in particular acetazolamide. Studies on car bonic anhydrase inhibitors led to the synthesis of benzothiadiazides which disclosed much less inactivating action on carbonic anhydrase and much more diuretic effect through an inhibition of tubular transport of sodium and chloride. Chlorothiazide was the first member of this class of diuretics. Thiazides are still used in clinical practice.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 636 pp. Englisch. Seller Inventory # 9780898388855
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Diuretics: Basic, Pharmacological, and Clinical Aspects : Proceedings of the International Meeting on Diuretics, Sorrento, Italy, May 26-30, 1986
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Buch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The need for adequate means by which to improve urine output is very old. Even in the 'Scuola Salernitana', the oldest medieval medical school in Western Europe, about 1000 years ago it was taught how to improve urine output. The list of known 'diuretica' included herbs, plants, roots, vegetables, in particular asparagus, fennel and carrot. The first diuretic drugs, however, were mercurial compounds. Thus, calomel, mercurous chloride, was initially used as a diuretic in the sixteenth century by Paracelsus, being one of the ingredients of the so-called 'Guy's Hospital pill'. But calomel had a cathartic effect so that it was replaced by organic mercurial compounds. These diuretics were clearly toxic. After the discovery of the car bonic anhydrase, in the early 1930s, and the introduction of sulfanilamide as a chemotherapeutic agent, it was observed that this drug was inhibiting carbonic anhydrase in vitro and urinary acidification in vivo thereby causing metabolic acidosis; urine output, however, appeared to increase. Subsequent studies led to the synthesis of more potent analogs, in particular acetazolamide. Studies on car bonic anhydrase inhibitors led to the synthesis of benzothiadiazides which disclosed much less inactivating action on carbonic anhydrase and much more diuretic effect through an inhibition of tubular transport of sodium and chloride. Chlorothiazide was the first member of this class of diuretics. Thiazides are still used in clinical practice. Seller Inventory # 9780898388855