Endocrine Neoplasms: 89 (Cancer Treatment and Research, 89) - Hardcover

Hardcover

ISBN 10: 0792343549 ISBN 13: 9780792343547

Publisher: Kluwer Academic Publishers, 1997

Synopsis

Andrew Arnold The past several years have been a time of intense excitement and have brought major advances in the understanding and treatment of endocrine neoplasms. This is therefore an excellent point at which to undertake a broad­ based overview of the state of the art in endocrine neoplasia for the Cancer Treatment and Research series. Because of the wide and interdisciplinary readership of this series, our aim for each chapter has been to provide ample background for those not highly familiar with the topic, while emphasizing the most recent advances. Furthermore, the chapters have been written with the clinician in mind, whether she or he is an oncologist, endocrinologist, surgeon, generalist, pathologist, or radiologist. As such, the authors' mission has been to focus on clinically relevant issues and to present the scientific basis of current or potential future advances in a manner easily digestible to the nonexpert. Endocrine tumors often cause problems for the patient by virtue of their hormonal activity, which may frequently (but certainly not always) over­ shadow the adverse consequences related to their mass per se. In fact, it is important to keep in mind that endocrine tumors can manifest two biologically separable but often intertwined properties, namely, increased cell mass and abnormal hormonal function. These need not go hand in hand, and their distinction has definite clinical relevance in, for example, the increasingly recognized problem of incidentally discovered adrenal or pituitary masses.

About this title

Synopsis

The late-1990s have been seen as a time of major advances in the understanding and treatment of endocrine neoplasms. The organization of this volume reflects both the organ-specific and more generalized aspects of endocrine tumourigenesis. Some chapters are focused on tumours of specific endocrine glands, for example, pituitary, para-thyroid, thyroid, and adrenal. More general themes in pathogenesis, diagnosis or treatment are also addressed, for example, in chapters on radiation-induced tumours, somatostatin analogs and receptors, persistent hyperinsulinemic hypoglycemia of infancy and paraneoplastic hypercalcemia. Finally, special issues of importance to the understanding and management of the familial endocrine tumour syndromes MEN-1 and MEN-2 are separately discussed.

Edition details

• Publisher: Kluwer Academic Publishers
• Publication date: 1997
• Language: English
• ISBN 10: 0792343549
• ISBN 13: 9780792343547
• Binding: Hardcover
• Number of pages: 464
• Editor: Arnold Andrew