Randomised Controlled Clinical Trials - Hardcover

Bulpitt, Christopher J.

Hardcover

ISBN 10: 0792342577 ISBN 13: 9780792342571

Publisher: Springer, 1996

Synopsis

After 13 years there are new areas to discuss and more recent trials to be included. Good clinical practice; evaluation of quality of life; measurement of the benefit:risk comparison; determination of cost- effectiveness and cost utility; stopping rules for trials; meta-analysis and subgroup analysis are all new sections. The references are expanded from 305 to 512 and include the recent advances in trial design, such as the n-of-1 trials and megatrials, and up-to-date examples to illustrate the points made in the 20 chapters.

About this title

Review

`...a well-written basic introduction to the design and conduct of a clinical trial, referring to many cardiovascular examples along the way. It especially singles out topics of quality of life and failures of previous randomised trials. With that in mind, it is a useful contribution to a very important area in medical research.'
Controlled Clinical Trials, 6 (1985)

Synopsis

After 13 years since the first edition there are new areas to discuss and more recent trials to be included. Good clinical practice; evaluation of quality of life; measurement of the benefit - risk comparison; determination of cost- effectiveness and cost utility; stopping rules for trials; meta-analysis and subgroup analysis are all new sections in this edition. The references are expanded from 305 to 512 and include the recent advances in trial design, such as the n-of-1 trials and megatrials, and up-to-date examples to illustrate the points made in the 20 chapters.

Edition details

• Publisher: Springer
• Publication date: 1996
• Language: English
• ISBN 10: 0792342577
• ISBN 13: 9780792342571
• Binding: Hardcover
• Edition number: 2
• Number of pages: 446