Statistical Methods in Diagnostic Medicine (Wiley Series in Probability and Statistics) - Hardcover

Zhou, Xiao–Hua; McClish, Donna K.; Obuchowski, Nancy A.

Hardcover

ISBN 10: 0471347728 ISBN 13: 9780471347729

Publisher: Wiley–Blackwell, 2002

Synopsis

An important role of diagnostic medicine research is to estimate and compare the accuracies of diagnostic tests. This book provides a comprehensive account of statistical methods for design and analysis of diagnostic studies, including sample size calculations, estimation of the accuracy of a diagnostic test, comparison of accuracies of competing diagnostic tests, and regression analysis of diagnostic accuracy data. Discussing recently developed methods for correction of verification bias and imperfect reference bias, methods for analysis of clustered diagnostic accuracy data, and meta-analysis methods, Statistical Methods in Diagnostic Medicine explains: Common measures of diagnostic accuracy and designs for diagnostic accuracy studies Methods of estimation and hypothesis testing of the accuracy of diagnostic tests Meta-analysis Advanced analytic techniques-including methods for comparing correlated ROC curves in multi-reader studies, correcting verification bias, and correcting when an imperfect gold standard is used Thoroughly detailed with numerous applications and end-of-chapter problems as well as a related FTP site providing FORTRAN program listings, data sets, and instructional hints, Statistical Methods in Diagnostic Medicine is a valuable addition to the literature of the field, serving as a much-needed guide for both clinicians and advanced students.

About this title

About the Author

XIAO HUA ZHOU is Professor in the Department of Biostatistics at the University of Washington and Director of the Biostatistics Unit in the HSR&D Center of Excellence at VA Puget Sound Health Care System. NANCY A. OBUCHOWSKI is Associate Staff at the Cleveland Clinic Foundation. DONNA K. McCLISH is Associate Professor of Biostatistics at Virginia Commonwealth University s Medical College of Virginia.

From the Back Cover

An important role of diagnostic medicine research is to estimate and compare the accuracies of diagnostic tests. This book provides a comprehensive account of statistical methods for design and analysis of diagnostic studies, including sample size calculations, estimation of the accuracy of a diagnostic test, comparison of accuracies of competing diagnostic tests, and regression analysis of diagnostic accuracy data. Discussing recently developed methods for correction of verification bias and imperfect reference bias, methods for analysis of clustered diagnostic accuracy data, and meta-analysis methods, Statistical Methods in Diagnostic Medicine explains:

• Common measures of diagnostic accuracy and designs for diagnostic accuracy studies
• Methods of estimation and hypothesis testing of the accuracy of diagnostic tests
• Meta-analysis
• Advanced analytic techniques?including methods for comparing correlated ROC curves in multi-reader studies, correcting verification bias, and correcting when an imperfect gold standard is used

Thoroughly detailed with numerous applications and end-of-chapter problems as well as a related FTP site providing FORTRAN program listings, data sets, and instructional hints, Statistical Methods in Diagnostic Medicine is a valuable addition to the literature of the field, serving as a much-needed guide for both clinicians and advanced students.

Edition details

• Publisher: Wiley–Blackwell
• Publication date: 2002
• Language: English
• ISBN 10: 0471347728
• ISBN 13: 9780471347729
• Binding: Hardcover
• Number of pages: 464