Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins (Methods of Biochemical Analysis)

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9780471191964: Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins (Methods of Biochemical Analysis)
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This volume aims to present a foundation for understanding the tools and resources available for the job of sequence analysis. Chapters introduce basic Internet concepts as they apply to molecular biologists and describe the major nucleotide, protein, and structural databases. Other coverage includes: sequence analysis packages; pairwise and multiple sequence comparisons; predictive methods for gene discovery; phylogenetic analysis; and mapping methods. They emphasize practical problem solving.

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Review:

"...a worthwhile addition to the library..." -- FEBS Letters, No, 468, 2000

"...this book is an excellent handbook with something for novice and expert alike. As its title suggests, if you want to get practical with bioinformatics, this book is for you..." -- Trends in Biotechnology, Volume 17, Number 10, 1999

"A reference that should be in the personal library of any biologist who uses the Internet for hte analysis of DNA and protein sequence data"--Science -- Science

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Bioinformatics A Practical Guide to the Analysis of Genes and Proteins Edited by Andreas D. Baxevanis and B. F. Francis Ouellette Bioinformatics, a field integrating molecular biology and computational methods has revolutionized gene discovery and related research. This new, rapidly evolving discipline provides the tools scientists need to cope with the flood of biological data and raw DNA and protein sequence information generated by such endeavors as the Human Genome Project. Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins makes computational biology accessible to scientists at all levels of expertise, including those with no formal computer training. It cuts through the overwhelming array of existing tools and databases, helping the reader design and implement a successful sequence analysis strategy. Presented by leading authorities in computational biology, this edited volume covers the gamut of topics, from using software and Internet resources to submitting DNA sequences to databases. Other topics include:
∗ The GenBank sequence database and structure databases
∗ Sequence analysis using GCG
∗ Information retrieval from biological databases
∗ The NCBI data model
∗ Sequence alignment and database searching
∗ Practical aspects of multiple sequence alignment
∗ Phylogenetic analysis
∗ Predictive methods using nucleotide sequences and protein sequences
∗ Navigating public physical mapping databases
∗ ACeDB: A database for genome information
Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins is fully referenced and provides appendices, sample sequence file formats, and over 120 illustrations. A must have for molecular biologists, geneticists, and any biologist interested in genes and proteins, it can also be used in a one–semester practical course on sequence analysis and bioinformatics.

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9780471324416: Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins (Methods of Biochemical Analysis)

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ISBN 10:  0471324418 ISBN 13:  9780471324416
Publisher: Wiley–Blackwell, 1998
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