Protein Engineering: A Practical Approach: No. 108 - Hardcover

Rees, Anthony R.

 
9780199631391: Protein Engineering: A Practical Approach: No. 108

Synopsis

Protein engineering is the rational modification or redesign of proteins using genetic engineering. Thus, it is now possible to modify enzyme specifities, remodel antibodies, and redesign many multi-domain proteins for therapeutic purposes. While the procedures for the introduction of mutations have become routine, predicting and understanding the effects of these mutations can be complicated. This volume provides a comprehensive guide to the methods used at every stage of the engineering process, from the choice of mutation strategy, through protein stability studies, to critical evaluations of mammalian, yeast, and bacterial host expression systems. It is a practical guide to this fascinating mixture of molecular biology, protein structure analysis, computation and biochemistry.

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9780199631384: Protein Engineering: A Practical Approach (The Practical Approach Series): 108

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ISBN 10:  0199631387 ISBN 13:  9780199631384
Publisher: Oxford University Press, USA, 1993
Softcover