Guidebook to the Secretory Pathway (Sambrook & Tooze Guidebook Series) - Hardcover

Rothblatt, Jonathan

Hardcover

ISBN 10: 0198599420 ISBN 13: 9780198599425

Publisher: Oxford University Press, 1994

Synopsis

This work aims to enable clinical non-specialists to rapidly gain access to unfamiliar work surrounding the secretory pathways. Detailing both the established and the experimental, the book outlines how recent work has established a role for the secretory pathway in the regulation of gene expression and cell-cycle control. Addressing many aspects of the secretory pathway, the book contains five sections: protein secretion in E.coli; translocation and maturation of newly synthesized polypeptides in the ER of eukaryotic cells; protein machines and catalyzing ER to golgi transport; membrane traffic in the golgi and to the cell surface; and membrane traffic to the lysosome/vacuole.

About this title

Review

this book will be welcomed in labs working on the secretory pathway, as it is the firt such components guide to become available and will help us keep track of all the SECs, VPSs, PEPs and COPs (Sean Munro, MRC Laboratory of Molecular Biology, TIBS, February 1995)

The strength of the book is that it collects a vast amount of published data in a readily accessible form. If you keep getting lost among the thickets of membrane traffic, this guidebook will lead you to safety. (Regis B. Kelly, University of California, San Francisco, Trends in Cell Biology, Vol 5, June 1995)

'...a most convincing approach for rapid and thorough information...The different entries of the catalogues are written by leading specialists in the respective field and they are all impressive in their preciseness, clarity and information density. The volumes shold be present in every biochemical laboratory and other institutions in the field of molecular and cell biology.' (G.Aumuller.)

About the Author

Jonathan Rothblatt is at Dartmouth College, Hanover. Peter Novick is at Yale University.

Edition details

• Publisher: Oxford University Press
• Publication date: 1994
• Language: English
• ISBN 10: 0198599420
• ISBN 13: 9780198599425
• Binding: Hardcover
• Number of pages: 296