This illustrated text provides undergraduate and postgraduate students with an accessible introduction to medicinal chemistry. It covers basic principles and background, and then describes the general tactics and strategies employed in developing an effective drug. Through the use of numerous examples, it highlights both the difficulties faced by the medicinal chemist and the great power and potential of rational drug design. This book is suitable for undergraduates on courses in chemistry (2nd and 3rd year) and medicinal chemistry (1st and 2nd year), and postgraduate chemists beginning work in pharmaceutical research.
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"The author has presented the subject material in a readable style at a appropriate level of chemical and biological sophistication....Chemical structures are well and carefully reproduced, and there many well-drawn diagrams and drawings which elucidate and complement the chemical and biological concepts discussed in the narrative."--Journal of Medicinal Chemistry "The author has presented the subject material in a readable style at a appropriate level of chemical and biological sophistication....Chemical structures are well and carefully reproduced, and there many well-drawn diagrams and drawings which elucidate and complement the chemical and biological concepts discussed in the narrative."--Journal of Medicinal Chemistry "The author has presented the subject material in a readable style at a appropriate level of chemical and biological sophistication....Chemical structures are well and carefully reproduced, and there many well-drawn diagrams and drawings which elucidate and complement the chemical and biological concepts discussed in the narrative."--Journal of Medicinal Chemistry "The author has presented the subject material in a readable style at a appropriate level of chemical and biological sophistication....Chemical structures are well and carefully reproduced, and there many well-drawn diagrams and drawings which elucidate and complement the chemical and biological concepts discussed in the narrative."--Journal of Medicinal Chemistry
Dr Graham Patrick gained his BSc Honours at Glasgow University, winning the McKay-Smith Prize for Chemistry. He completed his PhD with Professor Kirby and Professor Robins studying the biosynthesis of gliotoxin and related fungal metabolites. Following this, he worked in the pharmaceutical industry as a research chemist and radiochemist on a variety of projects that included topic areas such as opioids, antibacterial agents and antidepressants. His academic career has included positions at Leeds and Strathclyde Universities as well as the Australian National University. He joined the University of Paisley (now the University of the West of Scotland) in 1990, teaching medicinal chemistry and drug design.
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