Antigenic Variation - Hardcover

Hardcover

ISBN 10: 012194851X ISBN 13: 9780121948511

Publisher: Academic Press, 2003

Synopsis

The topic of antigenic variation is important in both biology and medicine. It is of enormous interest, as it describes the process(es) whereby microorganisms 'shift shape', by genetic rearrangement or otherwise. In medical terms, this has a major impact on the infectious disease process, since the immune system has great difficulty in keeping up with this variation, and thus eliminating the infectious agent. Antigenic variation is a major method by which microbes evade the immune response, and persist in the body.The broad scope of the book appeals to all those working in the field of infectious disease, immunology of infection, pathogenesis, molecular biology and also to evolutionary biologists. Topics covered include not only bacterial species, and viruses such as influenza, HIV, Rotavirus, but also eukaryotic parasites - one of the most fascinating groups of organisms exhibiting this behaviour.

Comprehensive coverage of antigenic variation from viruses to parasitesDiscussions devoted to molecular mechanisms of host evasionDetailed descriptions of host/pathogen interactions

About this title

About the Author

Edited by Alister G. Craig and Artur Scherf

Edition details

• Publisher: Academic Press
• Publication date: 2003
• Language: English
• ISBN 10: 012194851X
• ISBN 13: 9780121948511
• Binding: Hardcover
• Number of pages: 464
• Editor: Craig Alister G., Scherf Artur