The role of the Hr gene in brain, gut and thymus development in the mouse

Language: English

Published by Our Knowledge Publishing Aug 2021, 2021

6203500003 / 9786203500004

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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

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This item is printed on demand - it takes 3-4 days longer - Neuware -The mechanisms of genetic control of organ embryogenesis by WNT- and BMP-dependent gene networks have been studied only in general terms. However, the expression of many genes also involved in organogenesis correlates with the expression of genes of Wnt and Bmp families and their effectors. In particular, one of such genes is Hr (Hairless) gene. Mutation in the Hr gene in mice leads to the development of a characteristic phenotype expressed in complete baldness by three weeks of age. Also, adult mice carrying the mutant allele of the Hr gene in the homozygote show anatomical defects in the thymus, inner ear, brain and intestine, organs whose tissues express the normal Hr gene in heterozygotes and wild-type animals. The formation of these organs occurs during embryogenesis and is controlled by poorly understood molecular mechanisms. Inductive interactions between epithelial and mesenchymal components of embryonic setting play an important role in the regulation of their development.The aim of this work is to find out whether the normal allele of Hr gene affects the functioning of WNT- and BMP-dependent gene networks in the embryogenesis of epithelio-mesenchymal organs in mouse. 64 pp. Englisch.

Seller Inventory # 9786203500004

Title
The role of the Hr gene in brain, gut and thymus development in the mouse
Author
Olga Tacius
Publisher
Our Knowledge Publishing Aug 2021
Publication year
2021
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
6203500003
ISBN 13
9786203500004
Item weight
113 grams
Dimensions
220x150x4 mm

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

5-star seller

AbeBooks seller since January 11, 2012

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BuchWeltWeit Ludwig Meier e.K.

Germany