The multitasking molecular chaperone Hsp60
Language: English
Published by Elsevier Science, 2024
- Softcover
- New
Seller: moluna, Greven, Germanymoluna
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Condition: New
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Discusses strategies for diagnosis, patient monitoring, and treatment of disorders in which Hsp60 plays a role and can be used as biomarker and therapeutic target or agentExplains the fundamental biophysics, genetics, physiology, and pathog.
Seller Inventory # 1748611013
- Title
- The multitasking molecular chaperone Hsp60
- Publisher
- Elsevier Science
- Publication year
- 2024
- Condition
- New
- Binding
- Soft cover
- Language
- English
- ISBN 10
- 0443239967
- ISBN 13
- 9780443239960
Molecular mechanisms are briefly described with the purpose of illuminating roads toward accurate diagnosis, treatment, and patient monitoring. Consequently, the possibility of developing/applying chaperonotherapy centered on Hsp60, as a therapeutic tool or target, is analyzed in many sections of this book, across a variety of medical specialties. Over the last several years, the importance of the CS as a physiological system has been brought to prominence and its roles in health and disease made clear. The molecular chaperones, including Hsp60, are the key components of the CS that are typically cytoprotective, but they can also be etiopathogenic factors, causing diseases named chaperonopathies.
- Discusses strategies for diagnosis, patient monitoring, and treatment of disorders in which Hsp60 plays a role and can be used as biomarker and therapeutic target or agent
- Explains the fundamental biophysics, genetics, physiology, and pathogenicity of Hsp60
- Explores the mechanisms involving Hsp60 abnormalities causing disease, including carcinogenesis, inflammation, autoimmunity, and neurodegenerative disorders
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About the Author
Everly Conway de Macario is Adjunct Professor at the School of Medicine, University of Maryland at Baltimore, Baltimore, MD, USA. She has written 320 articles, authored 1 book and edited 8 books. Dr. Conway de Macario’s research interests include the development of the concept of sick chaperone or chaperonopathy as a factor contributing to the ageing process and disease, elucidation of the entire set of hsp70 genes in the human genome, and characterization of the whole complement of cct-Hsp60 genes in the human genome.
Alberto JL Macario is Adjunct Professor at the School of Medicine, University of Maryland at Baltimore, Baltimore, MD, USA. He has authored 380 articles, is the author of 1 book, and editor of 7 books. Dr. Macario is also Group Leader at the Euro-Mediterranean Institute of Science and Technology, Palermo, Italy. His current interests are chaperonopathies pertaining to Hsp60, Hsp10, and CCT genes/proteins.
"About the title" may belong to another edition of this title.
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