VIP, PACAP, and Related Peptides: From Gene to Therapy, Volume 1070 (Annals of the New York Academy of Sciences)
Language: English
Published by Wiley-Blackwell, Boston, 200
- First Edition
- Hardcover
- Used
Seller: Alien Bindings, BALTIMORE, MD, U.S.A.Alien Bindings
AbeBooks seller since April 3, 2019
Condition: Used - Very good
£ 51.67
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Rare hardcover edition. The covers look great. The binding is tight. The interior pages are clean and unmarked. The front flyleaf is scuffed. Electronic delivery tracking will be issued free of charge.
Seller Inventory # 10808
- Title
- VIP, PACAP, and Related Peptides: From Gene to Therapy, Volume 1070 (Annals of the New York Academy of Sciences)
- Author
- Vaudry, Hubert; Laburthe, Marc
- Publisher
- Wiley-Blackwell, Boston
- Publication year
- 200
- Condition
- Very Good
- Dust jacket
- No Jacket
- Binding
- Hardcover
- Language
- English
- ISBN 10
- 1573315508
- ISBN 13
- 9781573315500
- Edition
- First Edition.
- Dimensions
- 9.1 x 6.1 x 1.0 inches
VIP and PACAP are undoubtedly among the most fascinating neuropeptides ever identified. They belong to the largest family of regulatory peptides, which comprises several other prominent neuroendocrine peptides including secretin (the first peptide hormone that has been identified), glucagon, and growth hormone-releasing hormone. The structural and physiological relationships of these peptides as well as their receptors provide a unique model for investigating the processes of molecular evolution leading to the diversification of multigene families.
The primary structures of VIP and PACAP have been remarkably well conserved across vertebrates, suggesting that these peptides must be involved in vital functions throughout the animal kingdom. Indeed, VIP and PACAP appear to be implicated in a large array of physiological processes such as development; growth; endocrine, cardiovascular, respiratory, reproductive and digestive functions; immune responses; and circadian rhythms. There is also clear evidence that VIP and PACAP exert both trophic and antiproliferative effects on normal and tumor cells. The beneficial influence of VIP and PACAP agonists and antagonists in various pathological states including heart failure, ischemia, asthma, impotence, and cancer has motivated the development of novel selective VIP or PACAP ligands that could potentially be used as antihypertensive, neuroprotective, bronchodilatory, vasodilatory, and/or antiproliferative drugs. The occurrence of multiple VIP/PACAP receptor subtypes and splice variants that exhibit tissue-specific expression and possess differential affinity for various ligands generates hopes for the development of new therapeutic agents that could act selectively on the desired target cells.
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"Synopsis" may belong to another edition of this title.
About the Author
Hubert Vaudry is the editor of VIP, PACAP, and Related Peptides: From Gene to Therapy, Volume 1070, published by Wiley. Marc Laburthe is the editor of VIP, PACAP, and Related Peptides: From Gene to Therapy, Volume 1070, published by Wiley.
"About the title" may belong to another edition of this title.
Alien Bindings
BALTIMORE, MD, U.S.A.
AbeBooks seller since April 3, 2019
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Alien Bindings is an online bookshop located in Baltimore that has been in operation for nearly 20 years. Alien Bindings caters to the sciences including the physical sciences, astronomy, mathematics, computer science, the social sciences and medicine. I also dabble in a wide array of other categories including antiquarian books and history. I run a clean, green business. I try to reuse clean materials for packaging whenever possible. For example, books are carefully packaged frequently using clean cardboard for custom made boxes, recycled paper is used for printed labels and recycled plastic or bubble wrap is used for a weather-proof barrier. I drop the packages off to my local post office via foot or cycle in order to further reduce the carbon footprint.…
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caters to the sciences including the physical sciences, astronomy, mathematics, computer science, the social sciences and medicine. I also dabble in a wide array of other categories including antiquSeller's business information
Alien Bindings
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