TGF- Signaling (Hardcover)

Xin-Hua Feng

ISBN 10: 1493929658 / ISBN 13: 9781493929658

Published by Humana Press Inc., Totowa, NJ, 2015

About this Item

Hardcover. This volume details up-to-date information and attempts to take the reader into the exciting realm of TGF-b from the basic principles to the practical applications. Chapters provide basic introduction of TGF-b signaling from the cell surface to the nucleus, methods and techniques for the investigation of TGF-b signaling mechanism including receptors, Smads, intracellular kinases, microRNA, epigenetic regulation, post-translational regulations, non-Smad pathway; the physiological implications including those in cell cycle arrest, epithelial-mesenchymal transition, endothelial cells, adipogenesis, Th differentiation, stem cell, bone remodeling, ovary, zebrofish development, and frog animal capping; and the methodologies including metastasis imaging, 3D morphogenesis, membrane receptor quantification, conditional knockout, bone remodeling, kinase and phosphatase assays, BiFC interaction assays, and genome-wide siRNA screen. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, TGF-Beta Signaling: Methods and Protocols aims to ensure successful results in the further study of this vital field. Chapters provide basic introduction of TGF-b signaling from the cell surface to the nucleus, methods and techniques for the investigation of TGF-b signaling mechanism including receptors, Smads, intracellular kinases, microRNA, epigenetic regulation, post-translational regulations, non-Smad pathway; Shipping may be from multiple locations in the US or from the UK, depending on stock availability.

Seller Inventory # 9781493929658

Bibliographic Details

• Title: TGF- Signaling (Hardcover)
• Publisher: Humana Press Inc., Totowa, NJ
• Publication Date: 2015
• Language: English
• ISBN 10: 1493929658
• ISBN 13: 9781493929658
• Binding: Hardcover
• Edition: 1st Edition
• Condition: new

About this title

Synopsis

This volume details up-to-date information and attempts to take the reader into the exciting realm of TGF-β from the basic principles to the practical applications. Chapters provide basic introduction of TGF-β signaling from the cell surface to the nucleus, methods and techniques for the investigation of TGF-β signaling mechanism including receptors, Smads, intracellular kinases, microRNA, epigenetic regulation, post-translational regulations, non-Smad pathway; the physiological implications including those in cell cycle arrest, epithelial-mesenchymal transition, endothelial cells, adipogenesis, Th differentiation, stem cell, bone remodeling, ovary, zebrofish development, and frog animal capping; and the methodologies including metastasis imaging, 3D morphogenesis, membrane receptor quantification, conditional knockout, bone remodeling, kinase and phosphatase assays, BiFC interaction assays, and genome-wide siRNA screen. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

 

Authoritative and practical, TGF-Beta Signaling: Methods and Protocols aims to ensure successful results in the further study of this vital field.