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8°, early brown wrappers (upper splitting at joint; darkened). Title page foxed and browned; minor soiling on plates. In less than good condition. Manuscript index on recto of final flyleaf by a contemporary hand. Note about Araujo Carneiro (taken from Innocêncio) by a different hand laid in. (5 ll.) [missing half title?], xii, 136 pp., (1 l.), 4 hand-colored engraved plates. *** FIRST EDITION. Araujo Carneiro states, based on his observations in England, that the vaccine does not give immunity against smallpox and that vaccination itself has some dangers. The work earned its author the nickname "Dr. Bexigas." Araujo Carneiro's arguments were refuted decisively by Dr. Abrantes in the Investigador Portuguez in 1811. The colored plates show ulcers on a cow, a pig and two children. The Reflexoens was printed again in Lisbon, 1809 and in an English translation, London 1809 (Reflections and Observations on the Practice of Vaccine Inoculation).The Yale and Wellcome copies are described as having 7 preliminary leaves; other copies are described as having 6 preliminary leaves (Innocêncio, Faculdade de Medicina de Lisboa). This copy has only 5, but the signatures and the continuity of the text suggest that all that is missing is a half title.Araujo Carneiro (1776-1849), a Portuguese physician, fled to London when the French invaded. There he contributed to every issue of the enormously influential Correio Brasiliense, 1808-1822, and corresponded regularly with D. João. In 1812 he shocked society by eloping with the Marchioness de Alorna's daughter, who died soon thereafter. Although he was appointed chargé d'affaires to Switzerland in 1818, the Portuguese ministers refused to grant him a travel allowance, and he never reached his post. Soon afterwards he fell out of favor with D. João, and eventually became a follower of D. Miguel, who named him Visconde de Condeixa.*** Innocêncio III, 177 (without collation) and XI, 257 (calling for 12 unnumbered pages, xii, 136 pp., (1 l.), 4 plates). Wellcome II, 303: calling for 7 preliminary leaves. Lisbon, Faculdade de Medicina, Catálogo da collecção portuguesa I, 59: calling for 6 preliminary leaves. Pires de Lima, Catálogo da Bibliotheca da Escola Medico-Cirurgica do Porto 837: calling for xii, 136 pp. See also Borba de Moraes (1983) I, 156-57. Ferreira de Mira, Historia da medicina portuguesa p. 315. Porbase locates 3 copies, all at the Biblioteca Nacional de Portugal, and calls for 12, 136, (1) pp., [5] f., illus. NUC: CtY, DNLM.
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