Principles of automatic chemical analysis. Contained in: Standard Methods of Clinical Chemistry, Vol. 5, pp. 31-42, 1965.
Published by Academic Press, 1965., New York & London:, 1965
- First Edition
- Hardcover
- Used
Seller: Jeff Weber Rare Books, Neuchatel, Neuchatel, SwitzerlandJeff Weber Rare Books
AbeBooks seller since June 2, 2021
Condition: Used
£ 96.60
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Add to basketItem description from seller
8vo. xvii, 288 pp. Blue cloth, white-stamped cover and spine titles. Bookplate of Andras Gedeon. Very good. FIRST EDITION of THE INVENTION OF AUTOMATED CLINICAL ANALYSIS. "The automation technology introduced by Skeggs has become the indispensable backbone of modern clinical chemistry laboratories." [Gedeon]. "The autoanalyzer represented a significant advance in medical laboratory technology in the 20th century. This device, developed by Leonard T. Skeggs, ended the days in which laboratory technicians spent hours mixing reagents to test for substances in blood or urine. The autoanalyzer could perform over 20 tests in 24 seconds." "Leonard Skeggs earned his master's degree in 1941 and his PhD in 1948 in biochemistry at what would become Case Western Reserve University. He joined the faculty in 1950, became a full professor in 1969 and became emeritus professor in 1988. He was also director of the hypertension research laboratory at the Cleveland Veterans' Administration Hospital. Skeggs was affiliated with various well known Cleveland medical researchers including: Harry Goldblatt, a pioneer in hypertension research, Jack Leonards, a former head of the biochemistry department at CWRU, and Paul Berg who went on the win the Nobel Prize for his work on recombinant DNA." "Although Skeggs was involved in all of these important projects, his major accomplishment remains the autoanalyzer. Fed up with long waits in for blood sample tests, and confusion in the laboratory, Skeggs decided to look for a better way. He stated that, "One day it suddenly occurred to me that analyses could be done in a continuous flowing stream rather than batches or discretely." Skeggs set to work building his prototype. With borrowed money he bought the necessary materials. By 1951 a working model had been developed. Skeggs continuously improved and streamlined his design for the next 3 years. The instrument automatically mixed equal amounts of reagents and successive specimens and then measured the resulting color changes of each mixture." One of Skeggs' later designs, the sequential multiple analyzer with computer (SMAC) series, moved the state of the art from one test per specimen per minute to more than twenty tests every twenty-four seconds. The SMAC did its own calibrations and transmitted results directly to a laboratory computer. The results were highly accurate and reproducible, and the mechanization increased productivity and lowered costs." [Case Western Reserve University, Dittrick Medical History Center]. Gedeon, Science and technology in medicine, #81.10 (p. 417). …
Seller Inventory # S9535
Bibliographic details
- Title
- Principles of automatic chemical analysis. Contained in: Standard Methods of Clinical Chemistry, Vol. 5, pp. 31-42, 1965.
- Author
- SKEGGS, Leonard T. (1918- 2002).
- Publisher
- Academic Press, 1965., New York & London:
- Publication year
- 1965
- Binding
- Hardcover
- Edition
- 1st Edition
- Seller catalogs
- Chemistry
Jeff Weber Rare Books
Neuchatel, Neuchatel, Switzerland
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Jeff Weber Rare Books, established in 1986, relocated from California to Montreux, Switzerland in 2020. I specialize in the history of science, history of medicine, early printed books, fine printing, bibliography, Persia, fore-edge painting, scholarly books. I buy collections and do regular appraisal work.
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Medicine, history of, Natural history, Fore-edge paintings, Science, history of, Fore-Edge Painting, Bibliography, Fine printing, Travels to the Middle East; Persia; PhilosophyAssociation member
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Jeff Weber Rare Books
Switzerland
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