Predictive Toxicology: From Vision to Reality (Methods & Principles in Medicinal Chemistry)
Friedlieb Pfannkuch (Herausgeber), Laura Suter-Dick (Herausgeber), Raimund Mannhold (Series Editor), Hugo Kubinyi (Series Editor), & 1 mehr
Language: English
Published by Wiley-VCH, 2015
- First Edition
- Hardcover
- Used
Seller: suspiratio - online bücherstube lic.phil h.b., Basel, Switzerlandsuspiratio - online bücherstube lic.phil h.b.
AbeBooks seller since February 12, 2002
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SEHR GUT HARDCOVER, 404 PP.
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- Title
- Predictive Toxicology: From Vision to Reality (Methods & Principles in Medicinal Chemistry)
- Author
- Friedlieb Pfannkuch (Herausgeber), Laura Suter-Dick (Herausgeber), Raimund Mannhold (Series Editor), Hugo Kubinyi (Series Editor), & 1 mehr
- Publisher
- Wiley-VCH
- Publication year
- 2015
- Condition
- Sehr gut
- Binding
- Hardcover
- Language
- English
- ISBN 10
- 3527336087
- ISBN 13
- 9783527336081
- Edition
- 1. Auflage.
With a keen emphasis on novel approaches, the topics have been tackled by selected expert scientists, who are familiar with the theoretical scientific background as well as with the practical application of current methods. Emerging technologies in toxicity assessment are introduced and evaluated in terms of their predictive power, with separate sections on computer predictions and simulation methods, novel in vitro systems including those employing stem cells, toxicogenomics and novel biomarkers. In each case, the most promising methods are discussed and compared to classical in vitro and in vivo toxicology assays. Finally, an outlook section discusses such forward-looking topics as immunotoxicology assessment and novel regulatory requirements.
With its wealth of methodological knowledge and its critical evaluation of modern approaches, this is a valuable guide for toxicologists working in pharmaceutical development, as well as in safety assessment and the regulation of drugs and chemicals.
"Synopsis" may belong to another edition of this title.
About the Author
Laura Suter-Dick graduated as a biologist from the University of Buenos Aires (Argentina) and subsequently received her PhD from the Free University of Berlin (Germany). She has nearly 20 years of experience within the pharmaceutical industry, mainly in the field of toxicology. During her career in the pharmaceutical industry she worked as a scientist in the reproductive toxicology at Sandoz in Basel. She specialized in molecular toxicology (toxicogenomics) and in vitro assays at F. Hoffmann- La Roche Ltd., where she led the mechanistic toxicology. She has recently been appointed Professor for Molecular Toxicology at the Life Sciences School of the University of Applied Sciences and Arts Northwestern Switzerland. She acts as an external expert in several scientific panels and is also a Board Member of ESTIV (European Society of Toxicology in vitro).
"About the title" may belong to another edition of this title.
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