New Frontiers in Ultrasensitive Bioanalysis: Advanced Analytical Chemistry Applications in Nanobiotechnology, Single Molecule Detection, and Single Cell Analysis (Chemical Analysis: A Series of Monographs on Analytical Chemistry and Its Applications)

Oversized hardcover, xii + 308pp + 16 pages of glossy colour plates. Ex-foreign university library, withdrawn, internal library markings inside the front board and on the reverse of the title page. Pages are clean and bright throughout, with unmarked text, firmly bound. Boards show gentle handling wear; two small library labels on lower spine (contents obscured in black marker). Published without a dust jacket. -- Contents: 1. Is One Enough? (Andrew C. Beveridge); 2. Dissecting Cellular Activity from Single Genes to Single mRNAs (Xavier Darzacq); 3. Probing Membrane Transport of Single Live Cells Using Single Molecule Detection and Single Nanoparticle Assay (Xiao-Hong Nancy Xu); 4. Nanoparticle Probes for Ultrasensitive Biological Detection and Imaging (Amit Agrawal); 5. Tailoring Nanoparticles for the Recognition of Biomacromolecule Surfaces (Mrinmoy De); 6. Nanoscale Chemical Analysis of Individual Subcellular Compartments (Gina S. Fiorini & Daniel T. Chiu); 7. Ultra-sensitive Time-resolved Near-IR Fluorescence for Multiplexed Bioanalysis (Li Zhu & Steven A. Soper); 8. Ultrasensitive Microarray Detection of DNA using Enzymatically Amplified SPR Imaging (Hye Jin Lee); 9. Ultrasensitive Analysis of Metal Ions and Small Molecules in Living Cells (Richard B. Thompson); 10. Electrochemistry Inside and Outside Single Nerve Cells (Daniel J. Eves & Andrew G. Ewing); 11. New Bioanalytical Applications of Electrochemiluminescence (Yanbing Zu & Xiao-Hong Nancy Xu); 12. Single-Cell Measurements with Mass Spectrometry (Eric B. Monroe); 13. Outlooks of Ultrasensitive Detection in Bioanalysis (Xiao-Hong Nancy Xu) -- An overview of current research and developments in ultrasensitive bioanalysis. New platforms of ultrasensitive analysis of biomolecules and single living cells using multiplexing, single nanoparticle sensing, nano-fluidics, and single-molecule detection are advancing every scientific discipline at an unprecedented pace. With chapters written by a diverse group of scientists working in the forefront of ultrasensitive bioanalysis, this book provides an overview of the current status and an in-depth understanding of the objectives and future research directions of ultrasensitive bioanalysis. Spanning a wide spectrum of new research approaches, this book: Introduces new theories, ideas, methodologies, technologies, and applications of ultrasensitive bioanalysis in a wide variety of research fields; Includes background, fundamentals, and descriptions of instrumentation and techniques behind every experimental design and approach to help readers explore the promising applications of new tools; Covers single molecule detection (SMD), single living cell analysis, multi-functional nanoparticle probes, miniaturization, multiplexing, quantitative and qualitative analysis of metal ions and small molecules, and more Discusses techniques such as single molecule microscope and spectroscopy, single nanoparticle optics, single nanoparticle sensors, micro- and nano-fluidics, microarray detection, ultramicroelectrodes, electrochemiluminescence, mass spectrometry, and more. This book will be a useful resource and an inspiration for scientists and graduate and undergraduate students in a wide variety of research fields, including chemistry, biology, biomedical science and engineering, and materials science and engineering.…