Gene Genealogies, Variation and Evolution: A primer in coalescent theory (Paperback)

Hein

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Language: English

Published by Oxford University Press, Oxford, 2004

0198529961 / 9780198529965

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Paperback. Coalescent theory is a central concept in the study of genetic sequence variation that probabilistically describes the genealogy relating the sampled sequences. In this text, besides fulfilling the glaring need for such a book, the authors present this theory in a straightforward and elementary manner and describe the statistical and computational methods used in modelling and analyzing genetic sequence variation.Rich in examples andillustrations the book covers basic concepts, complications arising from geographical structure and recombination before considering aspects of statistical inference based on these models. The book ends withchapters on Gene Mapping, which combines sequence variation data with phenotypic data (such as disease) to define areas of the genome where genes are responsible for the trait, and Human Evolution, a research area that is experiencing a renaissance due to the enormous amounts of data produced in molecular studies.Authored by leading experts, this seminal text presents a straightforward and elementary account of coalescent theory, which is a central concept in the study ofgenetic sequence variation observed in a population. It is highly suitable for a graduate course in statistics, population, molecular and medical genetics, bioscience and medicine and studentsstudying the evolution of human population and disease, and will be an invaluable reference for bioscientists and statisticians in the pharmaceutical industry and academia Authored by leading experts, this seminal text presents an account of coalescent theory, which is a central concept in the study of genetic sequence variation observed in a population. It contains many examples and illustrations and is for a graduate course in statistics, population, molecular and medical genetics, bioscience and medicine. This item is printed on demand. Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability. …

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Title
Gene Genealogies, Variation and Evolution: A primer in coalescent theory (Paperback)
Author
Hein
Publisher
Oxford University Press, Oxford
Publication year
2004
Condition
new
Binding
Paperback
Language
English
ISBN 10
0198529961
ISBN 13
9780198529965
Edition
1st Edition

AussieBookSeller

Truganina, VIC, Australia

5-star seller

AbeBooks seller since June 22, 2007

Shipping rates from Australia to U.S.A.

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