The Brain Immune Axis and Substance Abuse

Sharp, Burt M.

ISBN 10: 0306450178 / ISBN 13: 9780306450174

Published by Plenum Pub Corp, New York, New York, U.S.A., 1995

a very good hardcover; an ex-library copy with usual markings; internally pages bright and clean; ---------- SATISFACTION GUARANTEED --------- FAST, COURTEOUS SERVICE ------ Size: 7 x 10". Seller Inventory # A51430

Synopsis:

1. Introduction: The Brain-Immune Axis: Role of Opiates and Other Substances of Abuse, the Hypothalmic-Pituitary-Adrenal Axis and Behavior.- 2. Detection of ?-Opioid Receptor mRNA in Immature T Cells.- 3. Identification of Opioid Receptors in the Immune System Using a Novel Combination of Selective Opioid Ligands and Indirect Phycoerythrin Immunofluorescence.- 4. Kappa Opioid Receptors on Three Related Thymoma Cell Lines: Differences in Receptor-Effector Coupling.- 5. Delta Opioid Agonists Inhibit Proliferation of Highly Purified Murine CD4+ and CD8+ T-Cells.- 6. Mitogenic Activation of Human T Lymphocytes Induces a High Affinity Morphine Binding Site.- 7. Morphine-Induced Suppression of Thymocyte Proliferation Is Mediated by Inhibition of I1-2 Synthesis.- 8. Active ?-Endorphin Metabolites Generated by T-Cell Ectopeptidases.- 9. The Cellular Basis for Opioid-Induced Immunosuppression.- 10. Endogenous Opioid Peptides Suppress Cytokine-Mediated Upregulation of HIV-1 Expression in the Chronically Infected Promonocyte Clone U1.- 11. Relevance of Opioid Bimodality to Tolerance/Dependence Formation: From Transmitter Release to Second Messenger Formation.- 12. Agonist Induced Constitutive Receptor Activation As a Novel Regulatory Mechanism: ? Receptor Regulation.- 13. Expression of Cannabinoid Receptor mRNA in Murine and Human Leukocytes.- 14. Cannabinoid Stimulation of Arachidonate Metabolism in Human Peripheral Blood Mononuclear Leukocytes.- 15. Marijuana, Receptors and Immunomodulation.- 16. Mouse Strain Differences in in vivo and in vitro Immunosuppressive Effects of Opioids.- 17. The Clastogenicity of Morphine Sulfate in vivo.- 18. Cellular Mechanisms Involved in Morphine-Mediated Suppression of CTL Activity.- 19. Evidence for the Involvement of Macrophage-Derived Nitric Oxide in the Immunomodulatory Effect of Morphine and Aversive Pavlovian Conditioning.- 20. Mechanisms Whereby Macrophage-Derived Nitric Oxide Is Involved in the Immunomodulatory Effects of Morphine.- 21. Effects of Central Administration of Morphine on Immune Status in Lewis and Wistar Rats.- 22. Morphine Alteration of Histamine Release in vivo.- 23. Effect of Chronic Morphine Treatment on Immune Responses to Keyhole Limpet Hemocyanin in Swine.- 24. SIV Mutations Detected in Morphine-Treated Macaca mulatta Following SIVmac239 Infection.- 25. Adjuvant Effects on Morphine-Induced Suppression of Immune Responses to MN rgp120/HIV-1 in Mice.- 26. Possible Mechanisms of Immunotoxicity Following in vivo Exposure to the Inhalant, Isobutyl Nitrite.- 27. Role of Immune Processes in Peripheral Opioid Analgesia.- 28. Chronic Treatment with Morphine and Ethanol, but Not Cocaine, Attenuates I1-1? Activation of FOS Expression in the Rat Hypothalamic Paraventricular Nucleus.- 29. Effects of r-Hu-Interferon-?2A in the Brain.- 30. Quantification of Macrophage-Derived Substance P Receptor mRNA Using Competitive Polymerase Chain Reaction.- 31. HIV-1 Heterogeneity and Cytokines: Neuropathogenesis.

About the Author: G. Thomas Sharp, Ph.D., has achieved national and international recognition as a Christian educator, religious leader, businessman and author. He is the founder and chairman of The Creation Truth Foundation (CTF) Inc., and founder of the Institute of Biblical Worldview Studies (IBWS), both in Noble, Oklahoma. He now speaks internationally at churches, schools, universities and conventions.

Friedman is Chairman and Distinguished Professor of Microbiology and Immunology at the University of South Florida College of Medicine.

Bibliographic Details

Title: The Brain Immune Axis and Substance Abuse
Publisher: Plenum Pub Corp, New York, New York, U.S.A.
Publication Date: 1995
Binding: Hard Cover
Condition: Very Good
Edition: First Edition.
Book Type: Ex-Library