The Blood-Brain Barrier - Biology and Research Protocols - Methods in Molecular Medicine

Language: English

Published by Humana Press, USA, 2003

1588290735 / 9781588290731

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  • Hardcover
  • New
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Brand New. Hardback copy in pictorial boards, no dustjacket as issued. 564pp. Illustrated throughout. Blood-brain barrier (BBB) breakdown leading to cerebral edema occurs in many brain diseases-such as trauma, stroke, inflammation, infection, and tumors-and is an important factor in the mortality arising from these con- tions. Despite the importance of the BBB in the pathogenesis of these diseases, the molecular mechanisms occurring at the BBB are not completely und- stood. In the last decade a number of molecules have been identified not only in endothelial cells, but also in astrocytes, pericytes, and the perivascular cells that interact with endothelium to maintain cerebral homeostasis. However, the precise cellular interactions at a molecular level in steady states and d- eases have still to be determined. The introduction of new research techniques during the last decade or so provide an opportunity to study the molecular mec- nisms occurring at the BBB in diseases. The Blood-Brain Barrier: Biology and Research Protocols provides the reader with details of selected morphologic, permeability, transport, in vitro, and molecular techniques for BBB studies, all written by experts in the field. Each part is preceded by a review that emphasizes the advantages and pitfalls of particular techniques, as well as offering much relevant current information. The techniques provided will be helpful to both beginners in BBB research and those more experienced investigators who wish to add a specific technique to those already available in their laboratories. (50/4).

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Title
The Blood-Brain Barrier - Biology and Research Protocols - Methods in Molecular Medicine
Author
Nag, Sukriti (edited)
Publisher
Humana Press, USA
Publication year
2003
Condition
New
Dust jacket
No Jacket
Binding
Hardcover
Language
English
ISBN 10
1588290735
ISBN 13
9781588290731
Edition
1st Edition

CURIO

Cleethorpes, North East Lincolnshire, United Kingdom

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CURIO was established in 1999 in Bingham, a town 10 miles from the city of Nottingham, Nottinghamshire, before relocating to Grimsby, North East Lincolnshire in 2007. As of 2025 we are now in Cleethorpes, North East Lincolnshire. We have a wide selection of stock comprising of first editions, fiction and non-fiction, signed and limited editions, children's books, and antiquarian books.

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