Structure Proteins Configurations Polypeptide Chains by Pauling Linus Robert Corey (3 results)

Soft cover. Condition: Very Good. 1st Edition. 8 pp, with 4 text figures. Stapled as issued. Crease in each blank, upper margin, else Very Good. First Edition. Author's offprint. "We are indebted to Prof. W. T. Astbury, Dr. I. MacArthur, Mr. F. H. C. Crick, and other workers in the field of the structure of proteins for having discussed with us the question of the structure of [alpha]-keratin. . . ." The first eight publications by Linus Pauling and Robert Corey on the alpha helix and pleated sheets of polypeptide chains appeared in the Proceedings of the National Academy of Sciences in April and May 1951. Linus Pauling was awarded the Nobel Prize in Chemistry in 1954 "for his research into the nature of the chemical bond and its application to the elucidation of the structure of complex substances.".

Soft cover. Condition: Very Good. 1st Edition. Pp. 729-740 with 7 text figures, and pp. 86-93 with 4 text figures. Original wrappers. Stapled as issued. Light creases in wrappers and text leaves. Red pencil name of former owner (J. Waser) on front wrapper. Very Good. First Edition. These two papers were issued in a single offprint. The first eight publications by Linus Pauling and Robert Corey on the alpha helix and pleated sheets of polypeptide chains appeared in the Proceedings of the National Academy of Sciences in April and May 1951. The two papers in this offprint were published not long after. Linus Pauling was awarded the Nobel Prize in Chemistry in 1954 "for his research into the nature of the chemical bond and its application to the elucidation of the structure of complex substances." NOTE about former owner Jurg Waser: "Born in 1916 in Zürich, Switzerland, Dr. Waser attended the University of Zürich and came to the United States in 1939 intending to spend a year on a graduate student exchange program at Caltech. The outbreak of war kept him in Pasadena, where he completed a Ph.D. in chemistry with Linus Pauling in 1944.".

1st Edition. FIRST EDITION OF THREE OF SEVEN PAPERS BY PAULING AND COREY ON THE MOLECULAR STRUCTURE OF PROTEINS. A decade before x-ray crystallography first revealed the structures of proteins, Pauling and Corey deduced their main structural features: the 'alpha-helix,' the 'gamma helix' and the 'beta sheet.' Their work had the same significance for proteins as the Watson and Crick papers (published two years later) had for the structure of DNA. "Instead of tackling the structure of an entire protein, the two scientists' efforts centered on discrete bits of proteins -- tiny crystals made up of repeating units called amino acids. When numberous amino acids link together to form chains, the chains assemble into one of several different configurations. Because an entire protein can encompass hundreds of these configurations folded into a tangled and sometimes impenetrable bundle, Pauling and Corey focused on elucidating the structure of each configuration one by one" (Brownlee, 'The Protein Papers,' on the PNAS at 100: Classics of the Scientific Literature, PNAS Website). "Pauling and Corey's research, now over a half-century old, guides today's biotechnology revolution and the search for hundreds of disease cures" (ibid). Linus Pauling was awarded the Nobel Prize in Chemistry in 1954 "for his research into the nature of the chemical bond and its application to the elucidation of the structure of complex substances" (ibid). CONDITION & DETAILS: Easton, PA: National Academy of Sciences. Two volume first edition Proceedings of the National Academy of Sciences, Vol. 37 and 38, 1951. Entire volumes. Quarto. (10 x 7 inches; 250 x 175mm). Bound in dark tan buckram, gilt-lettered at the spine. Moderate surface rubbing and scuffing. Tightly and very solidly bound. Bright and very clean throughout. Very good condition.