Methods Structural Analysis Protein (13 results)
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Taschenbuch. Condition: Neu. Biophysical Analysis of an Essential Regulator of the Immune System | Structural analysis of the RFX protein complex, a transcriptional regulator, using NMR methods | Latese Briggs | Taschenbuch | 124 S. | Englisch | 2011 | LAP LAMBERT Academic Publishing | EAN 9783845442600 | Verantwortliche Person…für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.
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Published by American Association of Pharmaceutical Scientists 2005
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Published by American Association of Pharmaceutical Scientists 2005
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hardcover. Condition: New. In shrink wrap. Looks like an interesting title.
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The human adaptive immune system serves as the primary defense against pathogens. While the human adaptive immune response is powered by many components, the Major Histocompatibility Class II (MHCII) molecules lie at the heart of the mac…hinery of the immune system. MHCII display of antigens triggers a cascade of events leading to the immune response. Lack of MHCII expression causes severe immunodeficiency disorders, whereas overproduction of these molecules can cause a variety of autoimmune diseases. The production of MHCII molecules is regulated by a multi-protein complex that includes the Regulatory Factor X (RFX) protein complex, which is comprised of three subunits, RFX5, RFXAP, and RFXB. Mutations or deletions in any RFX subunit that prevents the formation of the MHCII enhanceosome abolishes MHCII expression. A better understanding of how the RFX complex assembles will provide insight into the rational design of novel immunosuppressive therapeutic agents. Our structural analysis of the RFX complex elucidates this complex formation, in efforts to move towards this therapeutic goal.
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Language: English
Published by American Assoc. Of Pharm. Scientists Dez 2005 2005
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Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Protein pharmaceuticals form a fast-growing category in the arsenal of drugs. This book explores the nature of different analytical techniques and the way in which they are related to pharmaceutical proteins. In addition to serving the ana…lytical chemist, this book is needed by the formulation scientist who is responsible for design and formulation of a pharmaceutical protein that can be monitored during production and over time. 692 pp. Englisch.
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Buch. Condition: Neu. Methods for Structural Analysis of Protein Pharmaceuticals | Daan Crommelin (u. a.) | Buch | Biotechnology: Pharmaceutical Aspects | x | Englisch | 2005 | AAPS Press | EAN 9780971176720 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]sp…ringer[dot]com | Anbieter: preigu Print on Demand.
Language: English
Published by American Assoc. Of Pharm. Scientists Dez 2005 2005
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Buch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Protein pharmaceuticals form a fast-growing category in the arsenal of drugs. In the coming years, the patents on a number of the first-generation protein pharmaceuticals will expire, opening the door for the development of biogenerics into th…e market. However, it is very difficult to characterize these compounds so that the results can be replicated in a generic form. This volume details the nature of the different analytical techniques and how they are relevant for characterizing pharmaceutical proteins. In addition to serving the analytical chemist, this book is needed by the formulation scientist who is responsible for design and formulation of a pharmaceutical protein that can be monitored during production and over time. It also will be useful for students, fellows, and research scientists who are working in the academic world and in the pharmaceutical/biotechnology industry on basic aspects of proteins.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 692 pp. Englisch.
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Buch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Protein pharmaceuticals form a fast-growing category in the arsenal of drugs. In the coming years, the patents on a number of the first-generation protein pharmaceuticals will expire, opening the door for the development of biogenerics into the… market. However, it is very difficult to characterize these compounds so that the results can be replicated in a generic form. This volume details the nature of the different analytical techniques and how they are relevant for characterizing pharmaceutical proteins. In addition to serving the analytical chemist, this book is needed by the formulation scientist who is responsible for design and formulation of a pharmaceutical protein that can be monitored during production and over time. It also will be useful for students, fellows, and research scientists who are working in the academic world and in the pharmaceutical/biotechnology industry on basic aspects of proteins.
