Formulation Optimization Transdermal Patches by Rani Mukesh (11 results)
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Taschenbuch. Condition: Neu. Formulation and Optimization of Transdermal Patches | A brief study | Mukesh Rani (u. a.) | Taschenbuch | Englisch | 2025 | LAP LAMBERT Academic Publishing | EAN 9786208427764 | Verantwortliche Person für die EU: SIA OmniScriptum Publishing, Brivibas Gatve 197, 1039 RIGA, LETTLAND, customerservice[at…]vdm-vsg[dot]de | Anbieter: preigu.
Language: English
Published by LAP LAMBERT Academic Publishing Aug 2025, 2025
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 188 pp. Englisch.
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Paperback. Condition: new. Paperback. Lisinopril is an antihypertensive agent indicated for the prevention of hypertension, acute myocardial infarction and diabetic nephropathy. It is an angiotensin converting enzyme(ACE) inhibitor. It has a short half-life and undergoes variable first pass metabolism. It is required to be admin…istered two or three times daily which results in poor patient compliance. In this work an attempt was made to formulate & evaluate TDDS for sustained release of lisinopril by solvent evaporation method. Low molecular weight, good permeability and shorter half-life of the drug made it a suitable candidate for the development of trans dermal patch.The main objective of formulating the transdermal system was to prolong the drug release time, reduce the frequency of administration and to improve patient compliance. The compatibility characterization was done by IR method. By using 32factorial design nine formulations were prepared using hydrophilic (HPMC) andhydrophobic (ethyl cellulose) polymers along with selected plasticizer & permeationenhancer. PVA backing membrane was used as a substrate for pouring the polymeric solution. The prepared patches were evaluated for physical appearance, thickness. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.
Language: English
Published by LAP LAMBERT Academic Publishing Aug 2025, 2025
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Lisinopril is an antihypertensive agent indicated for the prevention of hypertension, acute myocardial infarction and diabetic nephropathy. It is an angiotensin converting enzyme(ACE) inhibitor. It has a short half-life and undergoes va…riable first pass metabolism. It is required to be administered two or three times daily which results in poor patient compliance. In this work an attempt was made to formulate & evaluate TDDS for sustained release of lisinopril by solvent evaporation method. Low molecular weight, good permeability and shorter half-life of the drug made it a suitable candidate for the development of trans dermal patch.The main objective of formulating the transdermal system was to prolong the drug release time, reduce the frequency of administration and to improve patient compliance. The compatibility characterization was done by IR method. By using 32factorial design nine formulations were prepared using hydrophilic (HPMC) andhydrophobic (ethyl cellulose) polymers along with selected plasticizer & permeationenhancer. PVA backing membrane was used as a substrate for pouring the polymeric solution. The prepared patches were evaluated for physical appearance, thickness.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 188 pp. Englisch.
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Lisinopril is an antihypertensive agent indicated for the prevention of hypertension, acute myocardial infarction and diabetic nephropathy. It is an angiotensin converting enzyme(ACE) inhibitor. It has a short half-life and undergoes var…iable first pass metabolism. It is required to be administered two or three times daily which results in poor patient compliance. In this work an attempt was made to formulate & evaluate TDDS for sustained release of lisinopril by solvent evaporation method. Low molecular weight, good permeability and shorter half-life of the drug made it a suitable candidate for the development of trans dermal patch.The main objective of formulating the transdermal system was to prolong the drug release time, reduce the frequency of administration and to improve patient compliance. The compatibility characterization was done by IR method. By using 32factorial design nine formulations were prepared using hydrophilic (HPMC) andhydrophobic (ethyl cellulose) polymers along with selected plasticizer & permeationenhancer. PVA backing membrane was used as a substrate for pouring the polymeric solution. The prepared patches were evaluated for physical appearance, thickness.
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