humana press mai 2008 (23 results)

Buch. Condition: Neu. Neuware -tetheunexpectedpassingofone ofourauthors,Dr.JosephHackettoftheFDA.Joe¿scontributionservesasa testimonytohisaccomplishmentsinthisfield,andhisinsightwillbemissed intheyearstocome.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 300 pp. Englisch.

Buch. Condition: Neu. Neuware -Prion Protein Protocols brings together a collection of current protocols in the field of mammalian prion disease research. Since identification of the prion protein gene some 20 years ago, what were once thought to be rare, neurodegenerative diseases of humans and animals have become a major research area. The major interest in this field results from the epidemic of bovine spongiform encephalopathy and the subsequent human prion disease, variant Creutzfeldt¿Jakob disease, which still poses an unknown risk to human health. The ¿unknowns¿ in the field stem from the enigmatic nature of infectious prions, the infectious agent that can transmit these diseases between individuals. Although much information has been gained over the past two decades about the molecular nature of prion proteins, only very recently have several research groups begun to cast light on how to turn the normal prion protein into its aberrant, infectious form. Prion Protein Protocols brings together a collection of protocols from 13 diff- ent laboratories in five countries covering basic science and diagnostic areas of prion research. Together, the chapters provide an up-to-date collection of current methods in this unique area of neuroscience. The notes section at the end of each methods chapter provides useful insight into the experimental techniques, and they are no doubt a benefit to researchers wanting to use these technologies.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 296 pp. Englisch.

Buch. Condition: Neu. Neuware -Molecular biology has transformed prenatal diagnosis because it permits an accurate diagnosis to be made from very small quantities of fetal material, even single cells. Although the latter permits the analysis of preimplantation embryos and, perhaps in the future, the analysis of fetal cells enriched from maternal blood, a major current focus is to facilitate rapid, cost-effective diagnoses. In this manner, the use of fluorescence in situ hybridization (FISH) or polymerase chain reaction (PCR)-based approaches on uncultured amniocytes or chorionic villi already permits a rapid assessment of the most common fetal aneuploidies (chromosomes 13, 18, 21, X, and Y) to be obtained within 24 h, thereby obviating the need for a 2-week culture period previously required for a traditional karyotype. Although the accuracy of karyotypic analysis is greatly enhanced by methodologies such as spectral karyotyping (SKY) or comp- ative genomic hybridization (CGH), the advent of high-density nucleotide arrays (chips) facilitates rapid assessment of the fetal genotype for a large number of mutations of frequent Mendelian disorders, e. g. , cystic fibrosis, the hemoglobinopathies, and Tay-Sachs syndrome. A further focus is the development of noninvasive, and hence, risk-free alternatives for prenatal diagnosis that no longer rely on invasive procedures such as amniocentesis or chorionic villus sampling. The most successful of these approaches is the analysis of placentally derived cell-free DNA in maternal blood.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 348 pp. Englisch.

Buch. Condition: Neu. Neuware -Not only is the quantity of life science data expanding, but new types of biological data continue to be introduced as a result of technological development and a growing understanding of biological systems. Methods for analyzing these data are an increasingly important component of modern biological research. In Bioinformatics, leading researchers in the field provide a selection of the most useful and widely applicable methods, able to be applied as is, or with minor variations, to many specific problems. Volume II: Structure, Function and Applications contains methods pertinent to the prediction of protein and RNA structures and the analysis and classification of structures, methods for inferring the function of previously identified genomic elements, chiefly protein-coding genes, medical applications in diagnostics and drug discovery, and 'meta-methods' for developers of bioinformatics algorithms.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 520 pp. Englisch.

Buch. Condition: Neu. Neuware -Not only is the quantity of life science data expanding, but new types of biological data continue to be introduced as a result of technological development and a growing understanding of biological systems. Methods for analyzing these data are an increasingly important component of modern biological research. In Bioinformatics, leading researchers in the field provide a selection of the most useful and widely applicable methods, able to be applied as is, or with minor variations, to many specific problems. Volume I: Data, Sequence Analysis and Evolution examines a selection of methods involving the generation and organization of data, including sequence data, RNA and protein structures, microarray expression data and functional annotations, methods for discovering the functional components of genomes, whether they be genes, alternative splice sites, non-coding RNAs or regulatory motifs, and several of the most interesting methods in phylogenetics and evolution.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 576 pp. Englisch.

Buch. Condition: Neu. Neuware -Oxidative Stress in Aging: From Model Systems to Human Diseases discusses the role of free radicals in aging in different animal models, as well as the relevance of free radicals on age-related diseases and pathological conditions in humans (following an introduction section of the basics and theory of free radicals). Human aging is a complex phenomenon - not everyone gets the same diseases and dies from the same cause. Accumulating reports implicate the connection between free radicals and various diseases and age-related pathological conditions. Although the causal relationships have not been established, it is necessary to discuss how free radicals are involved in each situation. In addition, the major interventions trials of antioxidant supplements in age-related disease, cancer and so forth are reviewed and discussed.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 336 pp. Englisch.

Buch. Condition: Neu. Neuware -Collecting an extensive amount of information from thousands of publications by leading investigators in this rapidly developing field, The Genetics and Molecular Biology of Neural Tumors provides a convenient and up-to-date one volume source for research in neural tumors of various cellular origins. Each chapter, with a comprehensive list of references and many informative tables, contains clinical and epidemiologic information, as well as succinct but relevant patho-histologic and immunohistochemical descriptions facilitating the interpretation of the findings on tumor genetics and molecular biology. With over 3,500 references, 110 figures and 120 tables, this volume gathers an astonishing body of knowledge regarding human neural tumors.As a ready and concentrated source, The Genetics and Molecular Biology of Neural Tumors is the perfect reference for busy clinicians, clinical investigators and laboratory researchers struggling through the copious and far-spread research on this subject.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 464 pp. Englisch.

Buch. Condition: Neu. Neuware -Over the last 30 years, pollution and its effects on the environment have emerged as leading topics of interest. The desire for positive action to restore and protect the environment is growing worldwide. How serious are particular types of pollution Is technology currently available to abate pollution And do the costs of abatement justify the degree of abatement achieved In the series, Handbook of Environmental Engineering, these questions are answered for the three basic forms of pollution and waste: gas, solid and liquid. Volume 7 in the series, Biosolids Engineering and Management, is a collection of methods of practical design, calculation and numerical examples that illustrate how organized, analytical reasoning can lead to the discovery of clear, direct solutions, especially in the areas of biosolids management, treatment, disposal and beneficial use. The book¿s distinguished panel of authors provides insight into a range of topics, including sludge and biosolids transport, pumping and storage, sludge conversion to biosolids, chlorination, stabilization, regulatory requirements, costs, agricultural land application, landfill, ocean disposal, combustion, incineration and sludge treatment process selection. Along with its sister book - Volume 6, Biosolids Treatment Processes ¿ Volume 7 is designed to be a basic biosolids treatment textbook, as well as a comprehensive reference book for advanced undergraduate and graduate students, designers of waste treatment systems, scientists and researchers. Both insightful and illuminating, Volume 7, Biosolids Engineering and Management gives state-of-the-art illustrations of the theory and practice of individual biosolids management systems and pertinent information on physical, chemical and biological treatment technologies used today.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 824 pp. Englisch.

Buch. Condition: Neu. Neuware -This timely volume addresses the areas of pathophysiology and therapy of pulmonary hypertension, which have seen exciting developments over the past decade. The discoveries of endothelin overexpression as well as prostacyclin and nitric oxide deficiency in association with pulmonary hypertension have led to important therapeutic insights. The new therapies have led to significant improvements in patient function, quality of life and survival. In this book, expert authors describe these new therapies. It will be of interest not only to cardiologists, pulmonary specialists and rheumatologists, but also many nurses and pharmacotherapists.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 464 pp. Englisch.

Buch. Condition: Neu. Neuware -As the global epidemic of diabetes continues to expand, the prevalence of type 2 diabetes is predicted to double in the next 20 years. Type 2 Diabetes Mellitus: An Evidence-Based Approach to Practical Management addresses this problem by expertly synthesizing the currently available evidence regarding specific issues in diabetes care. Written by an interdisciplinary team of scientists and medical professionals and comprising a wealth of information in a single resource, the book integrates the best evidence for the full range of clinical issues surrounding the evaluation and treatment of type 2 diabetes, including comorbid conditions such as hypertension, hyperlipidemia, and vascular disease. To quantify the strength of evidence supporting current practices, each chapter highlights related conditions, including fatty liver disease, pregnancy, and polycystic ovarian syndrome, and also addresses barriers to treatment, including stress, depression, and patient motivation.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 492 pp. Englisch.

Buch. Condition: Neu. Neuware -In Biotechnology for Fuels and Chemicals: The Twenty-Ninth Symposium, leading US and international researchers from academia, industry, and government exchange cutting-edge technical information and update current trends in the development and application of biotechnology for sustainable production of fuels and chemicals. This symposium emphasizes advances in biotechnology to produce high-volume, low-price products from renewable resources, while improving the environment. The major areas of interest include advanced feedstock production and processing, enzymatic and microbial biocatalysis, bioprocess research and development, opportunities in biorefineries, and commercialization of biobased products. International and domestic progress on producing liquid biofuels, especially ethanol and biodiesel, is highlighted, and related topics, including bioseparations and optimal integration of biochemical and thermochemical conversion technologies, are featured. Forward-looking and authoritative, Biotechnology for Fuels and Chemicals: The Twenty-NInth Symposium provides an illuminating overview of current research and development in the production of commodity fuels and chemicals from renewable biomass resources via biochemical and thermochemical routes.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 816 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Psychiatry has emerged as a burgeoning scientific field with major advances in etiology and treatment of several disorders. Just as there was excitement in the anatomic advances that took place a hundred years ago when Emil Kraepelin and his collaborators took on the enormous task of classification of psychiatric disorders based on rational scientific thinking, new advances in genetics, biochemistry, neuroanatomy and pharmacotherapy of mental disorders have brought us even closer to a better understanding of complex disorders like schizophrenia, bipolar disorder, depression and even autism. The major goal of the previous edition of this classic book was to update the busy clinician, psychiatric resident and medical student with the most up-to-date information on etiology, diagnosis and treatment of psychiatric disorders. This goal remains the focus of the third edition of this book. In this updated and expanded edition, the reader is provided with the most contemporary information and literature supported by a close survey of the field. Several new chapters dealing with new concepts in biology and treatment of mental disorders have been added. This new edition of this classic title, with its focus on biologic and medical aspects of psychiatry, will continue to be of significant help to all interested in the scientific practice of psychiatry. 799 pp. Englisch.