elsevier science jul 2017 (65 results)

Taschenbuch. Condition: Neu. Neuware -Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition explores thiamine and how its deficiency affects the functions of the brainstem and autonomic nervous system by way of metabolic changes at the level of the mitochondria. Thiamine deficiency derails mitochondrial oxidative metabolism and gives rise to the classic disease of beriberi that, in its early stages, can be considered the prototype for a set of disorders that we now recognize as dysautonomia. This book represents the life's work of the senior author, Dr. Derrick Lonsdale, and a recent collaboration with his co-author Dr. Chandler Marrs. 356 pp. Englisch.

Buch. Condition: Neu. Neuware.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Resilience is a biopsychosocial phenomenon-it encompasses personal, interpersonal, and community experiences. Innovative Approaches to Individual and Community Resilience reviews the current research and details differing levels and approaches to resilience. On a microlevel, this book specifies how to develop appropriate coping strategies, maintain cognitive flexibility, and identify, label, and share feelings before acting upon them. On a macrolevel, it defines and explores environmental resilience, social resilience, community resilience, and family resilience. It focuses on the importance of family, community, and spiritual bonds, in order to share experiences and enhance posttraumatic healing. The need to be firmly grounded in today, while learning from yesterday, in order to cope with the requirements of tomorrow is the primary emphasis of this book. 198 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Journeys in Science: Inspiring the Next Generation examines the STEM education pipeline and discusses important strategies on working through the various challenges that STEM trainees face. The book takes a look at career possibilities for scientists in the broadest sense, and is not solely limited to academia. Coverage includes individual and local concepts, as well as a discussion on how STEM education impacts trainee communities across the globe. The book also focuses on diversity in STEM and offers valuable insights based on the authors' own experiences. 130 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Healthcare Emergency Incident Management Operations Guide offers healthcare personnel a quick and intuitive guide to preparing for, responding to and recovering from events which have the potential to impact their operations. The recently updated Centers for Medicaid & Medicare Services (CMS) rules for emergency preparedness added 10-15 new healthcare organizations into the mix that require emergency preparedness efforts. The Hospital Incident Command System (HICS) is a good tool for event management but, like all tools, it requires practice. Many hospital personnel take online ICS courses and rarely practice enough to be proficient. This is a comprehensive guide to the HICS and can be referenced during initial and refresher training as well as during event management. 106 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Libraries and Key Performance Indicators: A Framework for Practitioners explores ways by which libraries across all sectors can demonstrate their value and impact to stakeholders through quality assurance and performance measurement platforms, including library assessment, evaluation methodologies, surveys, and annual reporting. Whilst several different performance measurement tools are considered, the book's main focus is on one tool in particular: Key Performance Indicators (KPIs). KPIs are increasingly being used to measure the performance of library and information services, however, linking KPIs to quality outcomes, such as impact and value can prove very difficult. This book discusses, in detail, the concept of KPIs in the broader context of library assessment and performance measurement. Through reviewing some of the applied theory around using KPIs, along with harvesting examples of current best practices in KPI usage from a variety of different libraries, the book demystifies library KPIs, providing a toolkit for any library to be used in setting meaningful KPIs against targets, charters, service standards, and quality outcomes. 164 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Considering the challenge of sustainability facing our society in the coming decades, catalysis is without any doubt a research area of major importance. In this regard, asymmetric organocatalysis, now considered a pillar of green chemistry, deserves particular attention. The first chapter of this volume examines the topic of asymmetric organocatalysis in light of radical chemistry. Recent important progress in this field has been attained by promoting the formation and harnessing the high reactivity of open-shell intermediates. Merging organocatalysis with radical chemistry has been the key to solving some longstanding bottlenecks, and has also significantly contributed to reinforcing the key role of organocatalysis in asymmetric catalysis. This chapter presents the most significant developments in this area, with a particular focus on asymmetric SOMO- and photoredox-organocatalyzed transformations. Chapter 2 focuses on quaternary ammonium salts (R4N+X-), especially chiral derivatives, and their behavior as unique catalysts in organocatalysis. Forming chiral ion-pairs capable of promoting asymmetric reactions, they also operate as unique 'transporters? involved in phase transfer catalytic processes between liquid-liquid or liquid-solid systems. Furthermore, they offer unique opportunities when forming cooperative ion-paired entities R4N+X-, allowing a synergistic implication of the counter-ion X- either as Brĝnsted bases or Lewis bases. Specific design of such chiral catalysts in modern chemistry and better insight into their mode of activation facilitates efficient and unprecedented chemical transformations. This chapter provides an overview of the use of chiral quaternary ammonium salts in organocatalysis, emphasizing both general mechanistic aspects and the scope of this approach. 184 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Saliva Protection and Transmissible Diseases provides a review of saliva protection, raising debate on micro-organisms potentially transmissible in saliva, and also considering the evidence on diseases that may be transmitted by kissing. Saliva is a complex body fluid essential to health, especially mastication, swallowing and speech, and hyposalivation can lead to dysfunction and even infection. More serious pathogens, such as herpes viruses and papillomaviruses can be conveyed by kissing, as can potentially lethal micro-organisms present in some saliva, such as meningococci, fungal organisms and Ebola viruses. 122 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Op Amps for Everyone, Fifth Edition, will help you design circuits that are reliable, have low power consumption, and can be implemented in as small a size as possible at the lowest possible cost. It bridges the gap between the theoretical and practical by giving pragmatic solutions using components that are available in the real world from distributors. The book does not just give a design with a transfer function; instead, it provides design tools based on transfer function, getting you to a working circuit so you can make the right decision on which op amp is best for the job at hand. With this book you will learn: single op amp designs that get the most out of every amplifier; which specifications are of most importance to your design, enabling you to narrow down the list of amplifiers to those few that are most suitable; strategies for making simple tweaks to the design-changes that are often apparent once a prototype has been constructed; how to design for hostile environments-extreme temperatures, high levels of shock, vibration, and radiation-by knowing which circuit parameters are likely to degrade and how to counteract that degradation. 484 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Synthesizing the latest research and treatment developments, Stepped Care for Borderline Personality Disorder: Making Treatment Brief, Effective, and Accessible aims to make treatment for borderling personality disorder (BPD) more accessible by providing clinicians with innovative brief and targeted intervention methods. Focusing on integrative treatment models, it offers clinicians a vital guide to the management of patients who are difficult to treat. Acknowleding the early developmental roots of BPD, the book includes sections on BPD in adolescence, childhood precursors of the disorder, and a broad range of etiological factors. It looks at the pitfalls clinicians face when trying to treat BPD, and offers a roadmap to avoiding them. 202 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Cognitive Development in Digital Contexts investigates the impact of screen media on key aspects of children and adolescents' cognitive development. Highlighting how screen media impact cognitive development, the book addresses a topic often neglected amid societal concerns about pathological media use and vulnerability to media effects, such as aggression, cyber-bullying and Internet addiction. It addresses children and adolescents' cognitive development involving their interactions with parents, early language development, imaginary play, attention, memory, and executive control, literacy and academic performance. 370 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The fourth edition of this classic work on circuit design gives you the understanding and practical know-how to produce optimized, reliable, cost-effective electronic circuits. It bridges the gap between the theoretical learning that most university courses provide and the practical knowledge and application that comes from years of experience. Topics covered include analog and digital circuits, component types, power supplies and printed circuit board design, plus new coverage of the latest advances in electronics since the previous edition published. The Circuit Designer's Companion is ideal for Professional electronics design engineers, advanced amateur electronics designers, electronic engineering students and professors looking for a book with a real-world design outlook. Updated with new material on: Extreme Environment Design Design for Reliability Wide Band Gap Devices for Power Electronics 496 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Treating Life-Threatening Bleedings: Development of Recombinant Coagulation Factor VIIa provides a comprehensive understanding of the first new drug within the area of hemostasis, describing a new mechanism of action that has resulted in a modified concept of the whole hemostasis mechanism. As the treatment of life-threatening bleedings is a serious challenge for clinicians, this powerful and historic case study presents a detailed roadmap on how a new medicine can be developed, stressing the interaction between science and clinical work. The book stresses the importance of patient care in the learning process and provides new ideas on how to approach diseases and their treatment. Users will find a real world example that will act as a timely resource for those learning about, or engaged in, performing and supervising research across the biomedical sciences. 214 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Biomaterials: A Systems Approach to Engineering Concepts provides readers with a systems approach to biomaterials and materials engineering. By focusing on the mechanical needs of implants, disease states, and current clinical needs, readers are encouraged to design materials and systems targeted at specific conditions, and to identify the impact of their proposed solutions. This inventive text is a useful resource for researchers, students, and course providers of biomaterials and biomedical engineering. 410 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Failures caused by electrostatic discharges (ESD) constitute a major problem concerning the reliability and robustness of integrated circuits and electronic systems. This book summarizes the many diverse methodologies aimed at ESD protection and shows, through a number of concrete studies, that the best approach in terms of robustness and cost-effectiveness consists of implementing a global strategy of ESD protection. ESD Protection Methodologies begins by exploring the various normalized test techniques that are used to qualify ESD robustness as well as characterization and defect localization methods aimed at implementing corrective measures. Due to the increasing complexity of integrated circuits, it is important to be able to provide a simulation in which the implemented ESD protection strategy provides the desired protection, while not harming the performance levels of the circuit. Therefore, the main features and difficulties related to the different types of simulation, finite element, SPICE-type and behavioral, are then studied. To conclude, several case studies are presented which provide real-life examples of the approaches explained in the previous chapters and validate a number of the strategies from component to system level. 284 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Neurobiological Background of Exploration Geosciences: New Methods for Data Analysis Based on Cognitive Criteria examines the neurobiological background of earth science disciplines. It presents the fundamental features of the human brain that form the cognitive basis of exploration geophysics and investigates how their analysis can drive the development of new brain-based technologies. Crucial aspects of human cognition include the impulse to explore the environment, the ability of our brain to create mental maps and virtual images of the world, and the human ability to recognize, integrate and save patterns of information in a shared memory. Geoscience technology can be made more effective by taking the working neurobiological principles of our brains into account. This book is appropriate for multiple audiences, including neuroscientists, cognitive scientists and geoscientists, presenting both theoretical and experimental results. 248 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Science of Crime Scenes, Second Edition offers a science-based approach to crime scenes, emphasizing that understanding is more important than simply knowing. Without sacrificing technical details, the book adds significantly to the philosophy and theory of crime scene science. This new edition addresses the science behind the scenes and demonstrates the latest methods and technologies with updated figures and images. It covers the philosophy of the crime scene, the personnel involved at a scene (including the media), the detection of criminal traces and their reconstruction, and special crime scenes, such as mass disasters and terroristic events. Written by an international trio of authors with decades of crime scene experience, this book is the next generation of crime scene textbooks. This volume will serve both as a textbook for forensic programs, and as an excellent reference for forensic practitioners and crime scene technicians with science backgrounds. 460 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The considerable growth of RFID is currently accompanied by the development of numerous identification technologies that complement those already available while seeking to answer new problems. Chipless RFID is one example.The goal is to both significantly reduce the price of the tag and increase the amount of information it contains, in order to compete with the barcode while retaining the benefits of a flexible reading approach based on radio communication.To solve the problem of the number of bits, this book describes the possibility of coding the information at the level of the overall shape of the RCS of the tag, which would facilitate reaching very large quantities. The design of the tags then returns to the resolution of the inverse problem of the electromagnetic signature. The proposed design methodology regularizes the problem by decomposing the signature on a basis of elementary patterns whose signature is chosen in advance. 222 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Ebola's Curse: 2013-2016 Outbreak in West Africa is about hemorrhagic fever viruses, especially Ebola, its initial origin in central Africa 1976, its unprecedented appearance in West Africa in 2013. The book records in sequence and detective style how the initial outbreak of Ebola from the index case in rural Guinea traveled to Sierra Leone, the work and fate of those working in the Kenema Government Hospital (KGH) isolation ward in Sierra Leone. The book provides vignettes of the three main players involved with Ebola at KGH, Sheik Khan, Pardis Sabeti, and Robert Garry. Khan was the head of the unit, declared a national hero by his Sierra Leone government. He died fighting Ebola and was/is recognized in the USA by American societies by awards created for his historic work and death. Pardis Sabeti, a geneticist from Harvard and Broad MIT Institute, who was honored as a 'Scientist of the Year' by Time Magazine and the Smithsonian Institute. Robert Garry, head of the operation to fight hemorrhagic fevers and Ebola, shuttled between Tulane University, KGH, and The White House to make aware through the press and others the dilemma and tragedy that was unfolding, and the need to obtain additional medical and health care support and supplies. Sabeti and Garry currently work with Oldstone on Ebola at KGH and thus personal communication and knowledge was/is available to the author for the book. 126 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Global Engineering Ethics introduces the fundamentals of ethics in a context specific to engineering without privileging any one national or cultural conception of ethics. Numerous case studies from around the world help the reader to see clearly the relevance of design, safety, and professionalism to engineers. Engineering increasingly takes place in global contexts, with industrial and research teams operating across national and cultural borders. This adds a layer of complexity to already challenging ethical issues. This book is essential reading for anyone wanting to understand or communicate the ethics of engineering, including students, academics, and researchers, and is indispensable for those involved in international and cross-cultural environments. 222 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Human Brain in Standard MNI Space: A Comprehensive Pocket Atlas is a thorough pocket atlas designed for easy reference and interpretation of medical and scientific MR-images. It is intended for both early career and advanced medical students, for residents in radiology and neurology, and those involved in neuroscience research, emphasizing anatomy's relationship to radiology. In addition, the book is ideal for non-specialists interested in issues relating to the brain or the determination of imaging features. 356 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Key Advances in Clinical Informatics: Transforming Health Care through Health Information Technology provides a state-of-the-art overview of the most current subjects in clinical informatics. Leading international authorities write short, accessible, well-referenced chapters which bring readers up-to-date with key developments and likely future advances in the relevant subject areas. This book encompasses topics such as inpatient and outpatient clinical information systems, clinical decision support systems, health information technology, genomics, mobile health, telehealth and cloud-based computing. Additionally, it discusses privacy, confidentiality and security required for health data. Edited by internationally recognized authorities in the field of clinical informatics, the book is a valuable resource for medical/nursing students, clinical informaticists, clinicians in training, practicing clinicians and allied health professionals with an interest in health informatics. 334 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Three-Dimensional Integrated Circuit Design, Second Eition, expands the original with more than twice as much new content, adding the latest developments in circuit models, temperature considerations, power management, memory issues, and heterogeneous integration. 3-D IC experts Pavlidis, Savidis, and Friedman cover the full product development cycle throughout the book, emphasizing not only physical design, but also algorithms and system-level considerations to increase speed while conserving energy. A handy, comprehensive reference or a practical design guide, this book provides effective solutions to specific challenging problems concerning the design of three-dimensional integrated circuits. Expanded with new chapters and updates throughout based on the latest research in 3-D integration: Manufacturing techniques for 3-D ICs with TSVs Electrical modeling and closed-form expressions of through silicon vias Substrate noise coupling in heterogeneous 3-D ICs Design of 3-D ICs with inductive links Synchronization in 3-D ICs Variation effects on 3-D ICs Correlation of WID variations for intra-tier buffers and wires 768 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Nanotechnology Methods for Neurological Diseases and Brain Tumors: Drug Delivery across the Blood-Brain Barrier compiles the latest (and future potential) treatment strategies for brain tumors and neurological diseases, in particular Alzheimer's, Parkinson's and stroke, those that bypass the blood/brain barrier. The current understanding of brain drug delivery and access is discussed in Chapter One, with the next section focusing on the implementation of the nose-to-brain intranasal route in brain-targeted drug delivery. In addition, nanotechnology-based brain drug delivery is covered in Chapter Three. This avenue offers impressive improvement in the treatment of neurological diseases and brain tumors by using bio-engineered systems that interact with biological systems at a molecular level. In Chapter Four, emphasis is placed on the need for brain-targeted experimental models that mimic disease conditions. Final chapters discuss the very latest advances in targeted treatment strategies for neurological diseases and brain tumors. 378 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Noradrenergic Signaling and Astroglia integrates what is known about the active role of astroglia in the locus coeruleus-noradrenergic system and outlines the most recent advances in the field. It discusses the molecular mechanisms underlying norepinephrine-induced receptor activation in astroglia, cellular metabolism and CNS energy provision, in vitro, ex vivo, and in vivo models, gliosignalling and neuronal activity, and astroglial networks, gap junctions, and morphological plasticity. The book also addresses the role of astroglial adrenergic receptor activation in memory formation, cognition, regulation of sleep homeostasis, and lastly in neurological disorders, including trauma (cellular edema), neurodegeneration (Alzheimer's disease), and neuroinflammation (multiple sclerosis). Noradrenergic Signaling and Astroglia is a valuable source of new knowledge for a wide audience, including graduate students, post-doctoral fellows, and researchers in neuroscience, life sciences, and the biological and biomedical sciences. 342 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Western Blotting Guru provides researchers in molecular biology with a handy reference for approaching and solving challenging problems associated with immunoblotting setup and optimization. As a laboratory guide, it emphasizes the technical aspects of efficiently employing immunoblotting as a tool in molecular biology laboratories. The book covers the basic science underlying immunoblotting and detailed description of the method parameters, followed by good benchtop practices, tips and tricks for obtaining high-quality data and a detailed troubleshooting guide addressing a variety of problem types. 100 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Decision-Making Management: A Tutorial and Applications provides practical guidance for researchers seeking to optimizing business-critical decisions employing Logical Decision Trees thus saving time and money. The book focuses on decision-making and resource allocation across and between the manufacturing, product design and logistical functions. It demonstrates key results for each sector with diverse real-world case studies drawn primarily from EU projects. Theory is accompanied by relevant analysis techniques, with a progressional approach building from simple theory to complex and dynamic decisions with multiple data points, including big data and lot of data. Binary Decision Diagrams are presented as the operating approach for evaluating large Logical Decision Trees, helping readers identify Boolean equations for quantitative analysis of multifaceted problem sets. Computational techniques, dynamic analysis, probabilistic methods, and mathematical optimization techniques are expertly blended to support analysis of multi-criteria decision-making problems with defined constraints and requirements. The final objective is to optimize dynamic decisions with original approaches employing useful tools, including Big Data analysis. Extensive annexes provide useful supplementary information for readers to follow methods contained in the book. 148 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition explores thiamine and how its deficiency affects the functions of the brainstem and autonomic nervous system by way of metabolic changes at the level of the mitochondria. Thiamine deficiency derails mitochondrial oxidative metabolism and gives rise to the classic disease of beriberi that, in its early stages, can be considered the prototype for a set of disorders that we now recognize as dysautonomia. This book represents the life's work of the senior author, Dr. Derrick Lonsdale, and a recent collaboration with his co-author Dr. Chandler Marrs. 356 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Board Review in Preventive Medicine and Public Health prepares physicians for their initial and recertification board exams in the related specialties of preventive, occupational and aerospace medicine. Formatted in a question and answer based style that imitates material on specialty exams, each question is linked to a detailed answer. The book contains over 640 question and answer sets covering areas such as general public health, health management, health law, community health, infectious disease, clinical preventive medicine, occupational medicine, aerospace medicine, environmental medicine, correctional (prison) medicine, emergency preparedness, epidemiology and biostatistics. The book is an essential board preparation for physicians with a background in the fields of preventive medicine, occupational medicine, and aerospace medicine. It is also useful for medical students, public health students and those wishing to gain an understanding of the key points in these fields. 450 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Spatial Econometrics provides a modern, powerful and flexible skillset to early career researchers interested in entering this rapidly expanding discipline. It articulates the principles and current practice of modern spatial econometrics and spatial statistics, combining rigorous depth of presentation with unusual depth of coverage. Introducing and formalizing the principles of, and 'need' for, models which define spatial interactions, the book provides a comprehensive framework for almost every major facet of modern science. Subjects covered at length include spatial regression models, weighting matrices, estimation procedures and the complications associated with their use. The work particularly focuses on models of uncertainty and estimation under various complications relating to model specifications, data problems, tests of hypotheses, along with systems and panel data extensions which are covered in exhaustive detail. Extensions discussing pre-test procedures and Bayesian methodologies are provided at length. Throughout, direct applications of spatial models are described in detail, with copious illustrative empirical examples demonstrating how readers might implement spatial analysis in research projects. Designed as a textbook and reference companion, every chapter concludes with a set of questions for formal or self--study. Finally, the book includes extensive supplementing information in a large sample theory in the R programming language that supports early career econometricians interested in the implementation of statistical procedures covered. 458 pp. Englisch.