Isbn: 9786137320099 - Internal Ribosome Entry Site: Ribosome, Nucleic Acid Sequence, Protein Biosynthesis, Eukaryote (3 results)

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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Please note that the content of this book primarily consists of articlesavailable from Wikipedia or other free sources online. An internalribosome entry site, abbreviated IRES, is a nucleotide sequence thatallows for translation initiation in the middle of a messenger RNAsequence as part of the greater process of protein synthesis. Usuallyin eukaryotes, translation can be initiated only at the 5' end of themRNA molecule, since 5' cap recognition is required for the assembly ofthe initiation complex. These sequences were first discovered in 1988 inpoliovirus RNA and encephalomyocarditis virus RNA in the labs of NahumSonenberg and Eckard Wimmer, respectively.…