Language: English
Published by New York Academy of Sciences, New York, 1998
ISBN 10: 1573311375 ISBN 13: 9781573311373
Seller: oz5457, Norridge, IL, U.S.A.
1998 NY Academy of Sciences hardcover; no dust jacket; withdrawn library copy with library markings/stickers; light cover wear; pages clean/tight; good condition.
Seller: Ria Christie Collections, Uxbridge, United Kingdom
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Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Interest in and emphasis upon different aspects of the sphingolipids have, in general, followed the biochemical developments of the day. The early inves tigators were preoccupied principally with the isolation of 'pure' compounds and structural elucidation. This historical perspective is found in the discus sion presented in Chapter 1 (Section 1. 1. 2 and Table III). Still, the isolation and structural characterization of glycolipids are the basic foundation of all our knowledge of enzymology, immunology, and cell biology. Recent infor mation obtained on structure has greatly affected the interpretation of various phenomena related to glycolipids. New structures suggest a new role of gly colipids as antigens and receptors. Ten years ago, only four neutral glycolipids and two gangliosides were known in human erythrocytes. We now know structures of at least twenty additional neutral glycolipids and ten additional gangliosides in human erythrocytes that are known to be important blood group, heterophil, and autoantigens. Erythrocytes are only one example of a cell type whose glycolipid profile has been extensively studied. Our defective knowledge in immunology and cell biology may be due to incomplete un derstanding of structural chemistry. Modern methodology based on methyla tion analysis, mass spectrometry, and enzymatic degradation has supple mented classical analysis based on clorimetry. Nuclear magnetic resonance spectroscopy is still in the development stage, but will eventually replace var ious chemical analyses. However, important future studies should be directed toward elucidating the organizational structure of glycolipids in membranes.
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Condition: Sehr gut. Zustand: Sehr gut | Seiten: 485 | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar.
Language: English
Published by Plenum Publishing Corporation, 1983
ISBN 10: 0306410923 ISBN 13: 9780306410925
Seller: Mispah books, Redhill, SURRE, United Kingdom
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Seller: Biblios, Frankfurt am main, HESSE, Germany
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. 1 Chemistry of Glycosphingolipids.- 1.1. Introduction.- 1.1.1. Classification and Nomenclature of Glycosphingolipids.- 1.1.2. Brief History of the Chemistry of Glycosphingolipids.- 1.2. Isolation of Glycosphingolipids.- 1.2.1. Extraction.- 1.2.2. Purificati.