Fleming Sir Alexander (37 results)

Condition: New.

Condition: New. In.

Soft cover. Condition: Very Good. 1st Edition. The Linacre Lecture delivered at Cambridge on May 6, 1946 by Sir Alexander Fleming. Uncommon first edition. Thin booklet with slight handling wear & small splits to covers at spine. 39pp.

Octavo hardcover (VG) in d/w (G+) jacket very tatty; all our specials have minimal description to keep listing them viable. They are at least reading copies, complete and in reasonable condition, but usually secondhand; frequently they are superior examples. Ordering more than one book may reduce your overall postage costs.

Condition: New. In.

c.294pp. 8vo. Original cloth, a little marked. Black and white plates; portrait frontis. Endpapers illustrated. A very good copy. First edition in English.

Soft cover. Condition: Good. stapled paperback, 8vo, 50pp, numerous photo illustrations, text clean and tight, no inscriptions, cover edges rubbed, Good condition.

Condition: Very Good. 1946. Hardback. Fine in original cloth covers, lacking dust wrapper. Covers showing some shelf wear and age. Lightly toned, a little spotting on edges, text is crisp and clear and remains a fine copy. . . . .

Condition: Very Good. 1946. Hardback. Fine in original cloth covers, lacking dust wrapper. Covers showing some shelf wear and age. Lightly toned, a little spotting on edges, text is crisp and clear and remains a fine copy. . . . . Books ship from the US and Ireland.

Soft cover. Condition: Very Good. 1st Edition. First edition. 8vo. pp. 39; very good in the original limp paper wrappers, sightly rubbed. "Penicillin, its antecedents, its discovery, its applications and properties, its increasing production, are here described by the discoverer, who also touches upon the future of this and similar substances, and issues a powerful please for the speedy endowment of microbiological research" (blurb from inside front wrapper).

Hardcover. Condition: Very Good. Dust Jacket Condition: No Jacket as Issued. Stated First Edition First Printing. Preface by author and dated July, 1946. Contents, General and Clinical. List of Illustrations (59). Acknowledgments by Butterworth. 362 pp. plus Index. fon on front pastedown. Textblock is sound and clean. Bookseller's Inventory# 240938.

Kl.-8°. 8 Bl. Blockbuchheftung in blaugrüner Färbung, 3 Abb. OBrosch., OU. Vorträge von I.P. Gerasimov, E. Neef, A. Watznauer, K.E. Rothschuh. - Acta Historica Aus dem Inhalt: Aufbau der Stoffe. Atomare Geschosse und Geräte zur Erzeugung von Nach der zweiten engl. Auflage ins Deutsche übertragen von Prof. A. Noll und Johanna Sprache: deutsch.

pp. 37, (i). 2 plates, 5 text figures. Original wrappers, a very good copy.

The Linacre Lecture 1946. Well-kept copy in tight binding; pages appear clean overall; jacket not price clipped. Used - Very Good. VG paperback in VG dust jacket.

Condition: New. Print on Demand.

ankfurt am Main, Büchergilde Gutenberg, 1863, 8°, 298 pp., orig. Leinenband mit Schutzumschlag.

hardcover. Condition: Befriedigend. Seiten; Sprache: Deutsch Gewicht in Gramm: 1.

Condition: New. PRINT ON DEMAND.

Original Wrappers. Condition: Very Good. Dust Jacket Condition: Very Good. First Edition. Includes a plea for "the speedy endowment of microbiological research".

Condition: Bueno. Editorial Saturnino Calleja. Madrid s/a. E. Tela editorial con sobrecubierta. 440 pp. 22x14.

First Edition. Very good copy in the original gilt-blocked cloth. Spine bands and panel edges somewhat dulled and rubbed as with age. Spine uniformly sun-toned. SIGNED and inscribed by E.B. Fleming. Remains quite well-preserved overall. Physical description: x p., 1 l., 380 p. : illus., diagrs. ; 23 cm. Series: Butterworth's medical publications. Notes: Includes bibliographies. Subjects: Penicillin Therapeutic use; Penicillin Pharmacology; Penicillin; Anti-Bacterial Agents; Penicillin - antibiotics - pharmacology. 1 Kg.

First Edition. Very good copy in the original gilt-blocked cloth. Spine bands and panel edges somewhat dulled and rubbed as with age. Spine uniformly sun-toned. SIGNED and inscribed by E.B. Fleming. Remains quite well-preserved overall. Physical description: x p., 1 l., 380 p. : illus., diagrs. ; 23 cm. Series: Butterworth's medical publications. Notes: Includes bibliographies. Subjects: Penicillin Therapeutic use; Penicillin Pharmacology; Penicillin; Anti-Bacterial Agents; Penicillin - antibiotics - pharmacology. 1 Kg.

Reprinted from The British Journal of Experimental Pathology, 1929. Vol. X, p. 226. Sm. 4to (250 x 186 mm). 12 pp. 4figures, 4 tables. Caption title. Stapled as issued; small chip to upper margin of first leaf, toning to edges, creased. Laid into blind-stamped red calf, black gilt-stamped leather spine label, forming a drop-back folding case. BOOK SIGNED BY ALEXANDER FLEMING. Very good. LIMITED REISSUE OF 250 COPIES OF FLEMING'S LANDMARK ANNOUNCEMENT OF THE DISCOVERY OF PENICILLIN. "In 1929, while working at St. Mary's Hospital in London, Fleming discovered the antibacterial properties of Penicillium mould. He published his findings in this present essay and suggested that the brown liquid substance produced by the mould would be an "efficient antiseptic for application to, or injection into, areas infected with penicillin-sensitive microbes." However, the substance proved to be unstable and chemically complex, and attempts to create a pure and stable drug by Fleming proved unsuccessful. In 1940, Ernst Chain and Howard Florey were able to stabilize the drug and work out suitable dosages for treatment." - Christie's. / First published in a very small edition (150) of which very few have survived, Fleming's 1929 paper did not have an immediate impact as he could not stabilize the drug to make it useful. With the announcement of Chain and Florey's successful tests of Penicillin in mice in 1940, Fleming received an outpouring of interest in his 1929 work and ordered an additional 250 copies printed (offered here). The first offprint is nearly unobtainable, and this 2nd issue scarce in its own right. / The original offprint issued by the British Journal of Experimental Pathology, was printed in 150 copies and issued in orange wrappers, with the pages numbered 226-236. That offprint, is rarely seen at auction, one copy sold for $ 126,750 in 2001 at Sotheby's. / Fleming shared the Nobel Prize for medicine in 1945 with Howard Florey (1898-1968) and Sir Ernst Chain (1906-1979), who extracted penicillin from the mould and were responsible for its commercial production. REFERENCES: Garrison and Morton, Norman 1933; Heirs of Hippocrates 2320; Norman 798; Printing and the Mind of Man, 420a. / ACCOMPANIED BY: FLEMING, Alexander, (editor.). Penicillin: Its Practical Application. Philadelphia: Blakiston, 1946. American issue. 8vo. x, 380 pp. Navy blue-stamped blue cloth; spine foot sticker residue. Very good. The book was prepared under the editorship of Sir Alexander Fleming, with 28 contributors, is a comprehensive and authoritative compendium of our present knowledge of penicillin in all its aspects. SIGNED by the author-editor, Alexander Fleming, on the title-page. / ACCOMPANIED BY THREE FLEMING OFFPRINTS OR REPRINTS: [With]: Lysozyme: President's Address. By Alexander Fleming. Reprinted from the Proceedings of the Royal Society of Medicine, December, 1932, Vol. XXVI. London: John Bale, etc., 1932. 14 pp. 2 figs. Publisher's gray-green printed wrappers. Fleming discovered lysozyme in 1922, described as a substance that "has potent antibacterial properties." / [With]: Streptococcal Meningitis Treated with Penicillin. . . [By] Alexander Fleming. Reprinted from The Lancet, Oct. 9, 1934. 12 pp. Caption title. Self-wraps; staining to outer margin. PRESENTATION COPY, stamped "WITH THE AUTHOR'S COMPLIMENTS." / [With]: Louis Pasteur. By Alexander Fleming. British Medical Journal, London Saturday, April 19, 1947. pp. 517-522. Caption title. Self-wraps, stapled at upper corner; creased. PROVENANCE: James Tait Goodrich. REFERENCES: See: Lax, Eric. The Mold in Dr. Florey's Coat: The Story of the Penicillin Miracle. 2015.

4to, pp.12, with halftone illustrations in the text; stapled as issued.Second edition of Fleming's study announcing the discovery of penicillin, one of 250 copies which Fleming commissioned to be printed in 1944. The original offprint, issued in 1929 in 150 copies and liberally distributed by Fleming to the scientific community at large for the prompt furthering of much-needed research, is now virtually unobtainable. In 1928, while working with culture plates of Staphylococcus bacteria at StMary's Hospital in London, Fleming noticed that some of his plates had become contaminated with a mould and that the bacterial colonies in contact with it had become transparent or dissolved. He reported his discovery in 1929 in a paper published in the British Journal of Experimental Pathology, naming the bactericidal substance 'penicillin' and proposing that an extract from it 'may be an efficient antiseptic for application to, or injection into, areas infected with penicillin-sensitive microbes'. However, as the substance proved too intractably unstable and Fleming remained unable to produce a stable and reliable drug, the paper failed to achieve an immediate impact. Only over a decade later, in 1940, did Ernst Chain and Howard Florey succeed in stabilising the drug and prescribing dosages for treatment. Provenance: The virologist Fred Himmelweit (19021977), who fled Germany in 1933, ending up in London with a job at the Wright-Fleming Institute at Saint Mary's Hospital, first under SirAlmroth Wright (18611947) and then under Fleming. There he studied viruses and the development of influenza vaccines, and eventually became director of the Department of Virus Research. Norman 799. See Garrison-Morton 1933; Heirs of Hippocrates 2320; One hundred Books famous in Medicine 96; and PMM 420a. Language: English.

London, Butterworth & Co., 1946, format in-8°, x pp + 380 pp, index. Original publisher's hardback (green cloth). No dustwrapper, spine a bit discoloured, some shelfwear, still a good/fine copy. No library markings.First edition.

LeatherBound. Condition: New. BOOKS ARE EXEMPT FROM IMPORT DUTIES AND TARIFFS; NO EXTRA CHARGES APPLY. Leatherbound edition. Condition: New. Leather Binding on Spine and Corners with Golden leaf printing on spine. Bound in genuine leather with Satin ribbon page markers and Spine with raised gilt bands. Pages: 476. A perfect gift for your loved ones. Reprinted from 1934 edition. NO changes have been made to the original text. This is NOT a retyped or an ocr'd reprint. Illustrations, Index, if any, are included in black and white. Each page is checked manually before printing. As this print on demand book is reprinted from a very old book, there could be some missing or flawed pages, but we always try to make the book as complete as possible. Fold-outs, if any, are not part of the book. If the original book was published in multiple volumes then this reprint is of only one volume, not the whole set. IF YOU WISH TO ORDER PARTICULAR VOLUME OR ALL THE VOLUMES YOU CAN CONTACT US. Resized as per current standards. Sewing binding for longer life, where the book block is actually sewn (smythe sewn/section sewn) with thread before binding which results in a more durable type of binding. Language: English Pages: 476.

London, Buttewrworth & Co. (Publishers), Ltd. Bell Yard, Temple Bar, July 1946, 8°, X, 380 pp., 59 Abbildungen, orig. Leinenband. First edition, first issue of the first printing of "the only book that Fleming prepared regarding his discovery of the antibiotic properties of penicillin". Norman Alexander Fleming made his discovery in 1928 and published his earliest paper on penicillin in 1929. But the substance was difficult to purify, and did not become available in large quantities until Howard Florey and Ernest Chain successfully mass-produced it at the beginning of the Second World War. It was during this conflict that penicillin proved its worth, successfully treating hundreds of thousands of Allied soldiers. This volume was published shortly after the war in the expectation that penicillin would soon be available commercially, but "there was not yet an authoritative British book for the guidance of the practitioner in its use" (preface). It contains an introduction by Fleming on his discovery of penicillin and 26 other essays on the history, manufacture, and clinical use of the drug by "experienced and eminent men" who were among the earliest to experiment with and prescribe it. A key work on the most significant medical breakthrough of the 20th-century, published while the therapy was still "very young and rapidly evolving". preface Printing and the Mind of Man 420; Garrison-Morton No.1933; Norman Libr. No. 800.

LeatherBound. Condition: New. BOOKS ARE EXEMPT FROM IMPORT DUTIES AND TARIFFS; NO EXTRA CHARGES APPLY. LeatherBound edition. Condition: New. Reprinted from 1848 edition. Leather Binding on Spine and Corners with Golden leaf printing on spine. Bound in genuine leather with Satin ribbon page markers and Spine with raised gilt bands. A perfect gift for your loved ones. Pages: 288 NO changes have been made to the original text. This is NOT a retyped or an ocr'd reprint. Illustrations, Index, if any, are included in black and white. Each page is checked manually before printing. As this print on demand book is reprinted from a very old book, there could be some missing or flawed pages, but we always try to make the book as complete as possible. Fold-outs, if any, are not part of the book. If the original book was published in multiple volumes then this reprint is of only one volume, not the whole set. Sewing binding for longer life, where the book block is actually sewn (smythe sewn/section sewn) with thread before binding which results in a more durable type of binding. Pages: 288.

LeatherBound. Condition: New. BOOKS ARE EXEMPT FROM IMPORT DUTIES AND TARIFFS; NO EXTRA CHARGES APPLY. LeatherBound edition. Condition: New. Reprinted from 1849 edition. Leather Binding on Spine and Corners with Golden leaf printing on spine. Bound in genuine leather with Satin ribbon page markers and Spine with raised gilt bands. A perfect gift for your loved ones. Pages: 264 NO changes have been made to the original text. This is NOT a retyped or an ocr'd reprint. Illustrations, Index, if any, are included in black and white. Each page is checked manually before printing. As this print on demand book is reprinted from a very old book, there could be some missing or flawed pages, but we always try to make the book as complete as possible. Fold-outs, if any, are not part of the book. If the original book was published in multiple volumes then this reprint is of only one volume, not the whole set. Sewing binding for longer life, where the book block is actually sewn (smythe sewn/section sewn) with thread before binding which results in a more durable type of binding. Pages: 264.

LeatherBound. Condition: New. BOOKS ARE EXEMPT FROM IMPORT DUTIES AND TARIFFS; NO EXTRA CHARGES APPLY. LeatherBound edition. Condition: New. Reprinted from 1923 edition. Leather Binding on Spine and Corners with Golden leaf printing on spine. Bound in genuine leather with Satin ribbon page markers and Spine with raised gilt bands. A perfect gift for your loved ones. Pages: 208 NO changes have been made to the original text. This is NOT a retyped or an ocr'd reprint. Illustrations, Index, if any, are included in black and white. Each page is checked manually before printing. As this print on demand book is reprinted from a very old book, there could be some missing or flawed pages, but we always try to make the book as complete as possible. Fold-outs, if any, are not part of the book. If the original book was published in multiple volumes then this reprint is of only one volume, not the whole set. Sewing binding for longer life, where the book block is actually sewn (smythe sewn/section sewn) with thread before binding which results in a more durable type of binding. Pages: 208.