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Language: English
Published by VDM Verlag 2008-11-19, 2008
ISBN 10: 3639091140 ISBN 13: 9783639091144
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Language: English
Published by VDM Verlag Dr. Müller, 2013
ISBN 10: 3639091140 ISBN 13: 9783639091144
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Kartoniert / Broschiert. Condition: New. The book presents an overview of the solid-statekinetic literature including methodologies used,mathematical derivations and pharmaceuticalapplications. The book investigates the relationship betweencalculation methods and arti.
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Language: English
Published by VDM Verlag Dr. Müller, 2008
ISBN 10: 3639091140 ISBN 13: 9783639091144
Seller: AHA-BUCH GmbH, Einbeck, Germany
Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The book presents an overview of the solid-statekinetic literature including methodologies used,mathematical derivations and pharmaceuticalapplications. The book investigates the relationship betweencalculation methods and artifactual results observedin solid-state kinetics. A new approach is proposedfor evaluating solid-state kinetic data, thisapproach combines modelistic and model-free methodsin a complimentary manner to achieve consistentkinetic results.Experimental data focused on studying the solid-statestability of several structurallyrelated solvates of sulfameter(5 methoxysulfadiazine), this was done by studyingthe kinetics of their desolvation reaction bothisothermally and nonisothermally. Calculated kineticparameters were compared and related to the crystalstructure of these solvates. A relationship wasestablished between desolvation kinetic parameters(e.g., activation energy) and the solvent size. Thesolid-state reaction models selected alsocorresponded to the single crystal structure of thesulfameter-solvate system.