Brian Pollo was born in Pasay City in 1994. After finishing his secondary education in Manila Science High School, he went on to obtain his B.S. Pharmacy degree from University of the Philippines College of Pharmacy (UPCP). In 2021, he finished the basic medical undergraduate curriculum and his internship at Philippine General Hospital. He is currently doing his MD-PhD (in molecular medicine) dissertation at University of the Philippines College of Medicine. He has been teaching biochemistry, pharmacology, and pharmaceutical science courses at UPCP and at The Manila Times College of Subic (TMTCS) since 2023.