Graduated with honours in Medicine and Surgery from the University of Parma, Italy, he specialised in Internal Medicine and Geriatrics. He served for 25 years as an internist at the Ospedale Maggiore of Parma, and then for 16 years as Chief of Medicine at the Hospital of Fidenza, Italy.
In 1981, he undertook a six-month clinical training and research fellowship at the Department of Medicine of McMaster University in Hamilton, Ontario, Canada, and subsequently returned to the same institution in 1987 and 1988, years in which the principles of Evidence-Based Medicine were being established.
He has conducted numerous randomised clinical trials and published dozens of scientific articles in international medical journals. He has been a Speaker and Chairman at various Italian and international scientific conferences, and has taught at the Universities of Parma and Perugia.