The alpha-1 Adrenergic Receptors

Language: English

Published by Springer Nature B.V. Jan 1988, 1988

0896031101 / 9780896031104

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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Neuware - During the past decade, great strides have been made in our un derstanding of the biochemistry and pharmacology of the alpha-l adrenergic receptor. The alpha-l adrenergic receptor plays a key role in biological function. This is evidenced by the fact that the alpha-l adrenergic receptor plays a prominent functional role in most organs of the body and in the key systems responsible for survival of the organism and maintenance of optimum biological activity. This is most apparent in the cardiovascular system, in which alpha-l adrenergic receptors are the single most important receptor involved in the maintenance of blood pressure and circu latory function. It is appropriate, therefore, that recent findings related to the pharmacology and biochemistry of the alpha-l adrenergic receptor be compiled, since this subject has not been reviewed in detail in recent years. It is the purpose of this book to present a series of reviews of key experimental findings that shed new light on the alpha-l adrenergic receptor and the manner in which it functions. Classically, most receptors have been characterized based on structure-activity relationships obtained for selective agonists and antagonists interacting with the receptor. Although there are many newer and more sophisticated approaches to receptor char acterization, structure-activity relationships still provide impor tant information regarding the chemical requirements made by the receptor for its occupation by ligands and its subsequent acti vation by those ligands possessing intrinsic efficacy and, there fore, agonist activity.

Seller Inventory # 9780896031104

Title
The alpha-1 Adrenergic Receptors
Author
Jr. Ruffolo
Publisher
Springer Nature B.V. Jan 1988
Publication year
1988
Condition
Neu
Binding
Buch
Language
English
ISBN 10
0896031101
ISBN 13
9780896031104
Item weight
968 grams
Dimensions
234x156x32 mm

AHA-BUCH GmbH

Einbeck, Germany

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