Virus-Like Particles : A Comprehensive Guide
Pumpens, Paul; Pushko, Peter
Sold by GreatBookPrices, Columbia, MD, U.S.A.
AbeBooks Seller since 6 April 2009
New - Hardcover
Condition: New
Ships within U.S.A.
Quantity: 10 available
Add to basketSold by GreatBookPrices, Columbia, MD, U.S.A.
AbeBooks Seller since 6 April 2009
Condition: New
Quantity: 10 available
Add to basketThis book represents the first complete and systematic guide to the virus-like particles (VLPs) and their applications as vaccines, therapeutic tools, nanomaterials, and nanodevices. The grouping of the VLPs follows the most recent virus taxonomy and the traditional Baltimore classification of viruses, which are based on the genome structure and mechanism of mRNA synthesis. Within each of the seven Baltimore classes, the order taxon serves as a framework of the chapter’s arrangement. The term "VLP" is used as a universal designation for the virus-, core-, or capsid-like structures, which became an important part of the modern molecular virology. The 3D structures, expression systems, and nanotechnological applications are described for VLPs in the context of the original viruses and uncover their evolving potential as novel vaccines and medical interventions.
Key Features
Paul Pumpens, PhD, graduated from the Chemical Department of the University of Latvia in 1970 and earned his PhD in molecular biology from the Latvian Academy of Sciences, Riga and DSc from the Institute of Molecular Biology of the USSR Academy of Sciences, Moscow, USSR. Dr. Pumpens started his research career as a research fellow at the Institute of Organic Synthesis, where he conducted research from 1973 to 1989. He served as head of the Laboratory of Protein Engineering at the Institute of Organic Synthesis (1989-1990), as head of the Department of Protein Engineering at the Institute of Molecular Biology of the Latvian Academy of Sciences (since 1993, the Biomedical Research and Study Centre) in Riga (1990-2002), and as scientific director of the Biomedical Research and Study Centre (2002-2014). He served as a professor of the Biological Department of the University of Latvia from 1999 until 2013. Dr. Pumpens pioneered genetic engineering research in Latvia. He was one of the first in the world to perform successful cloning of the hepatitis B virus genome and the expression of hepatitis B virus genes in bacterial cells. His major scientific interests are in designing novel recombinant vaccines and diagnostic reagents and development of tools for gene therapy based on virus-like particles. Dr. Pumpens is an author of more than 300 scientific papers and issues or pending patents. He has edited, together with Dr. Yury E. Khudyakov, the Taylor & Francis book Viral Nanotechnology (2015) and authored the Taylor & Francis book Single-stranded RNA phages: From molecular biology to nanotechnology (2020).
Dr. Peter Pushko graduated in 1984 from the University of Latvia, Riga, USSR and received his doctorate degree in Molecular Biology in 1990 from the University of Tartu (Tartu, Estonia) under mentorship of Dr. Paul Pumpens. He worked at the Institute of Molecular Biology (Riga, Latvia) on chimeric virus-like particles derived from bacteriophage fr and from hepatitis B virus. He completed postdoctoral studies at the Institute of Virology (Berlin, Germany), State Bacteriological Laboratory (Stockholm, Sweden) and Imperial Cancer Research Fund (Department of Pathology, University of Cambridge, U.K.) From 1994 to 2000, Dr. Pushko worked at the U.S. Army Medical Research Institute for Infectious Diseases (USAMRIID, Fort Detrick, Maryland, USA) as the National Research Council fellow. During this period, he developed RNA vector system from Venezuelan equine encephalitis (VEE) virus replicon and prepared experimental vaccines against Ebola, Marburg, and Lassa hemorrhagic fever viruses. In 2000-2010, Dr. Pushko worked at Novavax, Inc., (Rockville, MD), where he developed recombinant virus-like particles (VLPs) as vaccines against influenza. Since 2010, Dr. Pushko serves as the President and Chief Scientific Officer at Medigen Inc. (Frederick, Maryland), a biopharmaceutical company developing innovative vaccines for emerging infectious diseases and cancer. His scientific interests include vaccine development for emerging viruses, such as pandemic influenza, alpha-, arena-, and flaviviruses. He developed several novel vaccine technologies including VEE replicon vector, influenza VLPs, and DNA-launched live-attenuated vaccines. Dr. Pushko is the author of over 50 patents and 70 publications.
"About this title" may belong to another edition of this title.
Company Name: GreatBookPrices
Legal Entity: Expert Trading, LLC
Address: 6310 Stevens Forest, suite 200, Columbia MD 21046
Email address: CustomerService@SuperBookDeals.com
Phone number: 410-964-0026
consumer complaints can be addressed to address above
Registration #: 52-1713923
Authorized representative: Danielle Hainsey
If you are a consumer you can cancel the contract in accordance with the following. Consumer means any natural person who is acting for purposes which are outside his trade, business, craft or profession.
INFORMATION REGARDING THE RIGHT OF CANCELLATION
Statutory Right to cancel
You have the right to cancel this contract within 14 days without giving any reason.
The cancellation period will expire after 14 days from the day on which you acquire, or a third party other than the carrier and indicated by you acquires, physical possession of the the last good or the last lot or piece.
To exercise the right to cancel, you must inform us, GreatBookPrices, 6310 Stevens Forest Rd, Suite 200, 21046, Columbia, Maryland, U.S.A., 1 410-964-0026, of your decision to cancel this contract by a clear statement (e.g. a letter sent by post, fax or e-mail). You may use the attached model cancellation form, but it is not obligatory. You can also electronically fill in and submit a clear statement on our website, under "My Purchases" in "My Account". If you use this option, we will communicate to you an acknowledgement of receipt of such a cancellation on a durable medium (e.g. by e-mail) without delay.
To meet the cancellation deadline, it is sufficient for you to send your communication concerning your exercise of the right to cancel before the cancellation period has expired.
Effects of cancellation
If you cancel this contract, we will reimburse to you all payments received from you, including the costs of delivery (except for the supplementary costs arising if you chose a type of delivery other than the least expensive type of standard delivery offered by us).
We may make a deduction from the reimbursement for loss in value of any goods supplied, if the loss is the result of unnecessary handling by you.
We will make the reimbursement without undue delay, and not later than 14 days after the day on which we are informed about your decision to cancel with contract.
We will make the reimbursement using the same means of payment as you used for the initial transaction, unless you have expressly agreed otherwise; in any event, you will not incur any fees as a result of such reimbursement.
We may withhold reimbursement until we have received the goods back or you have supplied evidence of having sent back the goods, whichever is the earliest.
You shall send back the goods or hand them over to us or GreatBookPrices, 902B Paramount Pkwy, Ref: [transaction or order number], 60510, Batavia, Illinois, U.S.A., 1 410-964-0026, without undue delay and in any event not later than 14 days from the day on which you communicate your cancellation from this contract to us. The deadline is met if you send back the goods before the period of 14 days has expired. You will have to bear the direct cost of returning the goods. You are only liable for any diminished value of the goods resulting from the handling other than what is necessary to establish the nature, characteristics and functioning of the goods.
Exceptions to the right of cancellation
The right of cancellation does not apply to:
Model withdrawal form
(complete and return this form only if you wish to withdraw from the contract)
To: (GreatBookPrices, 6310 Stevens Forest Rd, Suite 200, 21046, Columbia, Maryland, U.S.A., 1 410-964-0026)
I/We (*) hereby give notice that I/We (*) withdraw from my/our (*) contract of sale of the following goods (*)/for the provision of the following goods (*)/for the provision of the following service (*),
Ordered on (*)/received on (*)
Name of consumer(s)
Address of consumer(s)
Signature of consumer(s) (only if this form is notified on paper)
Date
* Delete as appropriate.
Our warehouses across the globe are fully operational without substantial delays. We are working hard and continue to overcome the daily challenges presented by COVID-19. We appreciate your understanding.
Internal processing of your order will take about 1-2 business days. Please allow an additional 4-14 business days for Media Mail delivery. We have multiple ship-from locations - MD,IL,NJ,UK,IN,NV,TN & GA
| Order quantity | 8 to 14 business days | 5 to 14 business days |
|---|---|---|
| First item | £ 1.97 | £ 1.97 |
Delivery times are set by sellers and vary by carrier and location. Orders passing through Customs may face delays and buyers are responsible for any associated duties or fees. Sellers may contact you regarding additional charges to cover any increased costs to ship your items.