VISIONS OF THE CELL NUCLEUS (HB 2005). This item is unavailable.VISIONS OF THE CELL NUCLEUS (HB 2005)

Hemmerich and Diekmann (both of the Institute for Molecular Biotechnology, Germary) present an overview of the current understanding of nuclear cell biology, stressing the importance of recent interdisciplinary research embracing combinations of molecular biology, cell biology, genetics, biochemistry, biophysics, structural biology, and bioinformatics. Eighteen chapters review the literature regarding the ultrastructure of chromosome territories within the cell nucleus, the organization of the genome for its duplication and spatio-temporal regulation of DNA replication, the molecular machineries of cell mitosis, the architecture of gene domains and epigenetic regulation, the composition of transcription factories, the cotranscriptional processing of pre-mRNAs, the nuclear duties of the nucleolus, the structure of PML nuclear bodies and their dynamic protein constituents, the structure and functions of the Cajal Body, the interchromosomal domain compartment, the association of nuclear structure and function with various diseases, and a small group of new live cell and fluorescence imaging techniques. Annotation ©2005 Book News, Inc., Portland, OR (booknews.com)