Understanding Tertiary Interactions In Protein Structures : Use of Computational Methods and Techniques

Language: English

Published by LAP LAMBERT Academic Publishing, 2011

3843394032 / 9783843394031

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - Three-dimensional structures of proteins are the support of their biological functions.Their folds are stabilized by contacts between residues.Inner protein contacts are generally described through direct atomic contacts,while contact prediction methods mainly used inter-C distances. During the process of protein folding,the amino acid residues along the polypeptide chain interact with each other in a cooperative manner to form a stable native structure.The knowledge about inter-residue interactions in protein structures is helpful to understand the mechanism of protein folding and stability.It provides valuable insights for understanding protein folding and de novo protein design.I analyzed protein contacts on a high quality non-redundant pdbs drawn from protein databank using various criteria. I have computed the average number of contacts depending on the distance threshold to define a contact.Preferential contacts between types of amino acids have been highlighted. Detailed analysis have been done concerning the proximity of contacts in the sequence,the size of the proteins and fold classes.The strongest differences have been extracted,highlighting important residues.…

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Title
Understanding Tertiary Interactions In Protein Structures : Use of Computational Methods and Techniques
Author
Tejdeep Singh Bawa
Publisher
LAP LAMBERT Academic Publishing
Publication year
2011
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3843394032
ISBN 13
9783843394031
Item weight
113 grams
Dimensions
220x150x5 mm

AHA-BUCH GmbH

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