Tuberculosis Host-Pathogen Interactions

Ying Kong

ISBN 10: 303025383X / ISBN 13: 9783030253837

Published by Springer International Publishing Sep 2020, 2020

About this Item

This item is printed on demand - it takes 3-4 days longer - Neuware -This book summarizes the progress in studies of tuberculosis host-pathogen interactions from several perspectives: molecular microbiology, immunology, animal models, clinical studies, epidemiology, and drug discovery. Tuberculosis (TB) remains a severe global public health problem. Complex interactions between environmental, microbial and host factors lead to clinically relevant infections. Studies on bacterial virulence, host-genetic, and immunological factors contributing to the susceptibility to TB provide an ever-growing foundation of knowledge that is critical to finding new interventions. Studies of immune mechanisms against M. tuberculosis infection have identified immunological markers associated with specific phenotypes in the host, providing insight into how they may be used to augment current treatment strategies. Recent advances in diagnosis, therapeutics and vaccines, as well as basic-research oriented studies have shed light on the development of new directions for prevention, treatment and control of TB. Improved understanding of the interplay between the bacterium and host is a key component of reducing incidence worldwide. 264 pp. Englisch.

Seller Inventory # 9783030253837

Bibliographic Details

• Title: Tuberculosis Host-Pathogen Interactions
• Publisher: Springer International Publishing Sep 2020
• Publication Date: 2020
• Language: English
• ISBN 10: 303025383X
• ISBN 13: 9783030253837
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 235W x 155H x 15D millimeters 235 millimeters width by 155 millimeters height by 15 millimeters depth
• Weight: 406 grams

About this title

Synopsis

This book summarizes the progress in studies of tuberculosis host-pathogen interactions from several perspectives: molecular microbiology, immunology, animal models, clinical studies, epidemiology, and drug discovery.

Tuberculosis (TB) remains a severe global public health problem. Complex interactions between environmental, microbial and host factors lead to clinically relevant infections.  Studies on bacterial virulence, host-genetic, and immunological factors contributing to the susceptibility to TB provide an ever-growing foundation of knowledge that is critical to finding new interventions.  Studies of immune mechanisms against M. tuberculosis infection have identified immunological markers associated with specific phenotypes in the host, providing insight into how they may be used to augment current treatment strategies. Recent advances in diagnosis, therapeutics and vaccines, as well as basic-research oriented studies have shed light on the development of new directions for prevention, treatment and control of TB. Improved understanding of the interplay between the bacterium and host is a key component of reducing incidence worldwide. 

About the Author

Dr. Jeffrey D. Cirillo is a Regents’ Professor at Texas A&M University College of Medicine and the Director of the Center for Airborne Pathogens Research and Imaging with over 30 years of research in tuberculosis.

Dr. Ying Kong is an Assistant Professor at the University of Tennessee Health Science Center with over 16 years of research in tuberculosis.