Transient Receptor Potential Canonical Channels and Brain Diseases
Language: English
Published by Springer, 2018
Series: Book 289 of 544 - Advances in Experimental Medicine and Biology
- Softcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
AbeBooks seller since August 14, 2006
Condition: New
£ 209.80
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Add to basketItem description from seller
Druck auf Anfrage Neuware - Printed after ordering - This book discusses the latest findings on the physiological and pathological functions of transient receptor potential canonical/classical (TRPC) proteins in the brain.In additionto reviewing the functions of TRPCs in brain development and neuron transmission, it mainly covers the potential roles of TRPCs in brain disorders. TRPC proteins belong to the TRP channel superfamily, which has around 30 members. Just like TRP channels, TRPCs are non-selectively permeable to cations, with a selectivity of calcium over sodium that varies among different members. The TRPC subfamily consists of six members, grouped on the basis of the similarities in genesequence and proteinstructure in mammalians. What sets TRPCs apart from other subfamilies in TRPs is that their activation, stimulated by a membrane receptor-phospholipid C (PLC) cascade, contributes to the slow and sustained elevation of intracellular free calcium. Calcium ions, one of the most important types of second messengers, mediate a variety of physiological functions in the brain, including progenitor cell proliferation, dendritic formation, synaptic transmission and neuronal survival. All TRPCs except TRPC7 have been found in various regions of the brain, including the cerebrum, cerebellum, forebrain and hippocampus. This book provides students and investigators with comprehensive information on the regulation, function and potential of TRPCs and brain diseases in order to attract more attention to this field.…
Seller Inventory # 9789402414868
- Title
- Transient Receptor Potential Canonical Channels and Brain Diseases
- Author
- Yizheng Wang
- Publisher
- Springer
- Publication year
- 2018
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 940241486X
- ISBN 13
- 9789402414868
- Item weight
- 384 grams
- Dimensions
- 254x178x10 mm
- Series
- Book 289 of 544: Advances in Experimental Medicine and Biology
This book discusses the latest findings on the physiological and pathological functions of transient receptor potential canonical/classical (TRPC) proteins in the brain. In addition to reviewing the functions of TRPCs in brain development and neuron transmission, it mainly covers the potential roles of TRPCs in brain disorders.
"Synopsis" may belong to another edition of this title.
About the Author
Dr. Yizheng Wang is a senior investigator at the Institute of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences. He is the leader of the Laboratory of Neuronal Signal Transduction and an executive director of the Chinese Society for Neuroscience and Chinese Society of Biochemistry and Molecular Biology. His research focuses on the function and regulation of TRPC channels in neural development and diseases, a field in which he has published more than 40 research articles.
"About the title" may belong to another edition of this title.
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