Transient Processes in Cell Proliferation Kinetics

Andrej Yu. Yakovlev

ISBN 10: 3540518312 / ISBN 13: 9783540518310

Published by Springer Berlin Heidelberg, 1989

About this Item

Druck auf Anfrage Neuware - Printed after ordering - A mathematician who has taken the romantic decision to devote himself to biology will doubtlessly look upon cell kinetics as the most simple and natural field of application for his knowledge and skills. Indeed, the thesaurus he is to master is not so complicated as, say, in molecular biology, the structural elements of the system, i. e. ceils, have been segregated by Nature itself, simple considerations of balance may be used for deducing basic equations, and numerous analogies in other areas of science also superficial add to one's confidence. Generally speaking, this number of impression is correct, as evidenced by the very great theoretical studies on population kinetics, unmatched in other branches of mathematical biology. This, however, does not mean that mathematical theory of cell systems has traversed in its development a pathway free of difficulties or errors. The seeming ease of formalizing the phenomena of cell kinetics not infrequently led to the appearance of mathematical models lacking in adequacy or effectiveness from the viewpoint of applications. As in any other domain of science, mathematical theory of cell systems has its own intrinsic logic of development which, however, depends in large measure on the progress in experimental biology. Thus, during a fairly long period running into decades activities in that sphere were centered on devising its own specific approaches necessitated by new objectives in the experimental in vivo and in vitro investigation of cell population kinetics in different tissues.

Seller Inventory # 9783540518310

Bibliographic Details

• Title: Transient Processes in Cell Proliferation Kinetics
• Publisher: Springer Berlin Heidelberg
• Publication Date: 1989
• Language: English
• ISBN 10: 3540518312
• ISBN 13: 9783540518310
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 244W x 170H x 13D millimeters 244 millimeters width by 170 millimeters height by 13 millimeters depth
• Weight: 409 grams

About this title

Synopsis

This research monograph on the theory of unsteady cell kinetics based on stochastic and semi-stochastic models sets out to fill a gap in the literature. Specifically, considering the effect of transient processes in cell proliferation kinetics reveals new possible applications of the mathematical methods and also new regularity features of systems with induced cell proliferation. Thus for instance, a comprehensive analysis of the transition of hepatocytes to DNA synthesis and mitosis in regenerating rat liver is presented. Addressed primarily to researchers concerned with cell/tissue kinetics, the book can also be used by students knowing basic probability, as an introduction to the mathematics of cell proliferation kinetics.