Transacting Functions of Human Retroviruses
Language: English
Published by Springer Berlin Heidelberg, Springer Berlin Heidelberg Aug 2014, 2014
Series: Book 187 of 322 - Current Topics in Microbiology and Immunology
- Softcover
- New
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germanybuchversandmimpf2000
AbeBooks seller since January 23, 2017
Condition: New
£ 93.25
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Add to basketItem description from seller
This item is printed on demand - Print on Demand Titel. Neuware -The genome of retroviruses contains three major coding regions for virion proteins, gag, pol and env. Gag encompasses information for nonglycosylated viral proteins that form the matrix, the capsid and the nucleoprotein structures. From pol derive reverse transcriptase and integrase, and env codes for the surface glycoproteins of the virion which consist of a transmembrane and a surface domain, linked by disulfide bonds. A viral protease is derived eitherfrom the gagorfrom the pol coding region, depending on the virus. Simple retroviruses contain only this elementary gag, pol, and env coding information. Once integrated, they are able to multiply efficiently, using the cellular transcriptional and replication machineries without intervention of viral transacting factors. Most oncogenic retroviruses belong in this category. Complex retroviruses, on the other hand, encode additional nonstructural proteins from multiply spliced messages. These proteins play important regulatory roles in the life cycle of the virus. They function as transacting factors that, in concert with cellular regulatory proteins, control viral gene expression and function and are essential components in the replication of complex retroviruses. To this category belong the lentiviruses, the spumaviruses and a group of oncogenic retroviruses that includes human T cell leukemia virus (HTLV) and bovine leukosis virus(BLV).Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 256 pp. Englisch.…
Seller Inventory # 9783642789311
- Title
- Transacting Functions of Human Retroviruses
- Author
- Irvin S. Y. Chen
- Publisher
- Springer Berlin Heidelberg, Springer Berlin Heidelberg Aug 2014
- Publication year
- 2014
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 3642789315
- ISBN 13
- 9783642789311
- Item weight
- 394 grams
- Dimensions
- 235x155x15 mm
- Series
- Book 187 of 322: Current Topics in Microbiology and Immunology
"Synopsis" may belong to another edition of this title.
buchversandmimpf2000
Emtmannsberg, BAYE, Germany
AbeBooks seller since January 23, 2017
Shipping rates from Germany to U.S.A.
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