Toxicity Assessment Alternatives : Methods, Issues, Opportunities
Language: English
Published by Humana, 1999
- Hardcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
AbeBooks seller since August 14, 2006
Condition: New
£ 154.19
Quantity: 1 available
Add to basketItem description from seller
nach der Bestellung gedruckt Neuware - Printed after ordering - Toxicity Assessment Alternatives: Methods, Issues, Opportunities contains a broad array of critical surveys, contributed by active and respected investigators, describing their research and offering updates on toxicity assessment alternatives, directions determined by current and future grant programs, opportunities for mechanistically based test methods to detect endocrine disruptor activity, the use of alternatives in the Department of Defense hazard assessment initiatives, and the issues and opportunities for validation and regulatory acceptance. Several of these advances make use oftransgenic models that reduce the time and cost of carcinogenicity testing. Others use tissue cultures for the assessment of endocrine disrupting chemicals. Cultures of human epidermal keratinocytes are applicable as models for sulfur mustard lesions, and in vitro protein denaturation is used as a chemical test for assessing the ocular and dermal irritation potential of cosmetic prod ucts. Molecular modeling is applied to explaining chemical toxicity. Commercially developed assay systems have undergone extensive evaluation by their manufacturers. Some of these await external valida tion, and others await acceptance by North American and European regulatory agencies. Toxicity Assessment Alternatives: Methods, Issues, Opportunities provides information from members of the scientific and regulatory communities on what has been achieved and what has been accepted in alternatives to animal testing.…
Seller Inventory # 9780896037878
- Title
- Toxicity Assessment Alternatives : Methods, Issues, Opportunities
- Author
- Sidney A. Katz
- Publisher
- Humana
- Publication year
- 1999
- Condition
- Neu
- Binding
- Buch
- Language
- English
- ISBN 10
- 0896037878
- ISBN 13
- 9780896037878
- Item weight
- 573 grams
- Dimensions
- 235x157x21 mm
"Synopsis" may belong to another edition of this title.
From the Back Cover
Significantly extending the efforts the National Institutes of Health, the European Union, and the ICCVAM, Toxicity Assessment Alternatives offers all those evaluating toxicity today a cutting-edge collection of practical and highly effective alternative methods.
"About the title" may belong to another edition of this title.
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