Topological Data Analysis for Genomics and Evolution (Hardcover)

Raul Rabadan

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Language: English

Published by Cambridge University Press, Cambridge, 2019

1107159547 / 9781107159549

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Hardcover. Biology has entered the age of Big Data. A technical revolution has transformed the field, and extracting meaningful information from large biological data sets is now a central methodological challenge. Algebraic topology is a well-established branch of pure mathematics that studies qualitative descriptors of the shape of geometric objects. It aims to reduce comparisons of shape to a comparison of algebraic invariants, such as numbers, which are typically easier to work with. Topological data analysis is a rapidly developing subfield that leverages the tools of algebraic topology to provide robust multiscale analysis of data sets. This book introduces the central ideas and techniques of topological data analysis and its specific applications to biology, including the evolution of viruses, bacteria and humans, genomics of cancer, and single cell characterization of developmental processes. Bridging two disciplines, the book is for researchers and graduate students in genomics and evolutionary biology as well as mathematicians interested in applied topology. Algebraic topology is particularly suited for the analysis of high dimensional large data sets, including those in modern biology. The book introduces geometric and topological methods, including statistics, as well as applications to biology - including cancer genetics, single cell studies and reconstructing evolutionary relationships from genomic data. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.…

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Title
Topological Data Analysis for Genomics and Evolution (Hardcover)
Author
Raul Rabadan
Publisher
Cambridge University Press, Cambridge
Publication year
2019
Condition
new
Binding
Hardcover
Language
English
ISBN 10
1107159547
ISBN 13
9781107159549

CitiRetail

Stevenage, United Kingdom

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