Thymic Development and Selection of T Lymphocytes (Current Topics in Microbiology and Immunology, 373, Band 373)
Language: English
Published by Springer, 2013
Series: Book 220 of 322 - Current Topics in Microbiology and Immunology
- Hardcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
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- Title
- Thymic Development and Selection of T Lymphocytes (Current Topics in Microbiology and Immunology, 373, Band 373)
- Author
- Thomas Boehm
- Publisher
- Springer
- Publication year
- 2013
- Condition
- Neu
- Binding
- Hardcover
- Language
- English
- ISBN 10
- 3642402518
- ISBN 13
- 9783642402517
- Item weight
- 383 grams
- Dimensions
- 241x160x14
- Series
- Book 220 of 322: Current Topics in Microbiology and Immunology
The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place. Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.
"Synopsis" may belong to another edition of this title.
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