Three clustering algorithms and their application to microarray data : A Study of Three clustering algorithms and their application to microarray data

Language: English

Published by LAP LAMBERT Academic Publishing, 2010

3838347943 / 9783838347943

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nach der Bestellung gedruckt Neuware - Printed after ordering - In the context of medical diagnostics, an important problem is to find the genes that are correlated with given phenotypes. These genes may reveal insights to biological processes and may be used to predict the phenotypes associated to samples of RNA. To that end, two new clustering methods are presented and studied. Our first algorithm allows us to analyze cell evolution by observing how the state of every gene changes over time. Our second algorithm cluster genes whose expression profiles are similar by using a classification of the samples utilized in the microarray experiments. This classification is based upon one or more conditions that affect the composition of the samples analyzed. By using the label of the microarray experiments,extra information is provided to cluster genes. The research reported here on the first two algorithms presented consists of three parts: 1. testing our methods on artificial datasets sampled from the probabilistic models on which our methods are based, 2. using our methods on microarray expression datasets to cluster genes, 3. and comparing results from parts 1 and 2 with the results obtained by other clustering methods on the same datasets.

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Title
Three clustering algorithms and their application to microarray data : A Study of Three clustering algorithms and their application to microarray data
Author
Francisco Javier Molina Lopez
Publisher
LAP LAMBERT Academic Publishing
Publication year
2010
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3838347943
ISBN 13
9783838347943
Item weight
161 grams
Dimensions
220x150x7 mm

AHA-BUCH GmbH

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