Therapeutic Kinase Inhibitors: 355 (Current Topics in Microbiology and Immunology, 355) [Hardcover] [Mar 22, 2012] Mellinghoff, Ingo K. and Sawyers, Charles L.
Language: English
Published by Springer, 2012
Series: Book 151 of 322 - Current Topics in Microbiology and Immunology
- Hardcover
- New
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- Title
- Therapeutic Kinase Inhibitors: 355 (Current Topics in Microbiology and Immunology, 355) [Hardcover] [Mar 22, 2012] Mellinghoff, Ingo K. and Sawyers, Charles L.
- Publisher
- Springer
- Publication year
- 2012
- Condition
- New
- Binding
- Hardcover
- Language
- English
- ISBN 10
- 3642282954
- ISBN 13
- 9783642282959
- Series
- Book 151 of 322: Current Topics in Microbiology and Immunology
Cancer drug development is currently undergoing a profound shift. Drugs targeting fundamental cellular processes such DNA-replication and microtubule function, often referred to as “chemotherapy” and still the backbone of most cancer treatment regimens, are increasingly being complemented by or replaced with kinase inhibitors. This new class of drugs targets enzymes which provide growth and survival signals to cancer cells by transferring phosphate groups from Adenosine-5'-triphosphate (ATP) to other proteins, lipids, nucleotides, and carbohydrates.
This book summarizes the current state of kinase inhibitor therapy for cancer. Successful drug development relies on the expertise and dedication of many experts. To reflect this team approach to finding new kinase inhibitors and defining their optimal use for cancer treatment, the editors invited experts in academia and pharmaceutical industry to share their insights into various aspects of this process, ranging from the first chemical screens, to preclinical testing and disease-focused clinical drug development. The editors and authors hope these lessons will be instructive for the novice as well as the expert.
"Synopsis" may belong to another edition of this title.
From the Back Cover
Cancer drug development is currently undergoing a profound shift. Drugs targeting fundamental cellular processes such DNA-replication and microtubule function, often referred to as “chemotherapy” and still the backbone of most cancer treatment regimens, are increasingly being complemented by or replaced with kinase inhibitors. This new class of drugs targets enzymes which provide growth and survival signals to cancer cells by transferring phosphate groups from Adenosine-5'-triphosphate (ATP) to other proteins, lipids, nucleotides, and carbohydrates.
This book summarizes the current state of kinase inhibitor therapy for cancer. Successful drug development relies on the expertise and dedication of many experts. To reflect this team approach to finding new kinase inhibitors and defining their optimal use for cancer treatment, the editors invited experts in academia and pharmaceutical industry to share their insights into various aspects of this process, ranging from the first chemical screens, to preclinical testing and disease-focused clinical drug development. The editors hope these lessons will be instructive for the novice as well as the expert.
"About the title" may belong to another edition of this title.
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StainesBookHub aim to offer our customers a variety of the old & latest Books. With the Experience of more than 15 Years, we always keep an eye on the latest trends in Books and put our customers' wishes first, we try our best to give books to our customers on lowest prices. We ship Books through Fedex Priority. That is why we have satisfied customers all over the world, and are thrilled to be a part of the Books industry. StainesBooksHub also sell books in Bulk, We try our best to Provied High Quality, Fast Service, Global Shipping.
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