Techniques to Investigate Mitochondrial Function in Neurons

Language: English

Published by Springer New York, Springer US Aug 2018, 2018

1493983296 / 9781493983292

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This item is printed on demand - Print on Demand Titel. Neuware -This volume describes a broad spectrum of experimental approaches for investigating structure, function, and transport of neuronal mitochondria in health and disease. Most of these approaches were only recently developed and range from electron tomography-based 3D reconstruction of mitochondrial cristae to patch clamp recording from mitochondria in intact neurons. The chapters in this book cover topics such as mitochondrial proteomics, fluorescence lifetime imaging, respirometry and mitophagy, as well as optical approaches based on the use of genetically engineered fluorescent sensors for monitoring synaptic ATP and axonal ROS generation, mitochondrial Ca2+ cycling and pH changes, and mitochondrial dynamics and axonal trafficking in live neurons. Each chapter also discusses difficulties, tips, tricks, and precautions to take. Neuromethods series style chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.Cutting-edge and comprehensive, Techniques to Investigate Mitochondrial Function in Neurons is a valuable and useful resource for a broad range of investigators interested in the function of neuronal mitochondria in health and disease states.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 360 pp. Englisch.

Seller Inventory # 9781493983292

Title
Techniques to Investigate Mitochondrial Function in Neurons
Author
Yuriy M. Usachev
Publisher
Springer New York, Springer US Aug 2018
Publication year
2018
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
1493983296
ISBN 13
9781493983292
Item weight
677 grams
Dimensions
254x178x20 mm

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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